Objective: To observe the correlation between vaginal flora and sex hormone levels in postmenopausal vaginitis. Methods: Totally 30 patients with postmenopausal bacterial vaginitis were selected as the experimental group, and 30 postmenopausal healthy subjects were selected as the control group. The vaginal pH value, flora density, diversity and sex hormone levels were compared between the two groups. Results: The pH value of postmenopausal patients with bacterial vaginitis was higher than that of the control group(P＜0.05), the bacterial density of the Gram-positive bacteria group was lower than that of the control group(P＜0.05), and the bacterial diversity was higher than that of the control group(P＜0.05), the bacterial density of gram-negative bacilli and positive cocci was higher than that of the control group(P＜0.05), the levels of luteinizing hormone(LH), follicle-stimulating hormone(FSH) and prolactin(PRL) were higher than those of the control group, and estradiol(E2), progesterone(PRGE) and testosterone(TESTO) were lower than those of the control group, the differences between the two groups were statistically significant(P＜0.05), that was the higher the postmenopausal E2, PRGE and TESTO, the lower the PRL, and the higher the concentration of Gram-positive bacteria. Conclusion: The flora density of Gram-positive bacteria in the vaginal microecology of postmenopausal women is correlated with sex hormones.
LIU Jun
,
XIAO Huiying
,
Yi Jilemuren
,
REN Xiaomin
,
XUE Jiawei
,
DAN Yuting
,
YU Haiting
. Study on the correlation between flora density and sex hormonesin postmenopausal vaginitis[J]. Journal of Baotou Medical College, 2025
, 41(7)
: 82
-86
.
DOI: 10.16833/j.cnki.jbmc.2025.07.015
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