Objective: To explore the clinical effect of continuous nursing measures on postoperative rehabilitation of patients with lower limbs ASO interventional therapy.Methods: The control group was treated with routine health education nursing, while the observation group was added with continuous nursing measures on the basis of the control group.Results: The life quality scores in observation group were higher than those in control group at 3rd, 6th and 12th month after discharged (P＜0.05). The incidence of vascular restenosis and vascular stenosis in observation group were lower than those in control group (P＜0.05). The nursing satisfaction rate in observation group was 89.41 % (76/85), which was higher than that in control group (72.94 %, 62/85) (P＜0.05).Conclusion: The use of continuous nursing in postoperative rehabilitation of patients with ASO can improve the patients' quality of life, reduce the incidence of vascular restenosis and vascular stenosis, and improve the patients' satisfaction with nursing.

Objective: To investigate the affecting factors about the morbidity of gestational diabetes mellitus (GDM), and to put forward its preventive measures.Methods: The relevant information of 82 cases of GDM and 184 cases of healthy pregnant from March 2010 to March 2016 were collected. The univariate and multivariate Logistic regression was used to analyze the demographic characteristics, behavior customs and the relationship with GDM, and the pregnant outcomes were compared between the two groups.Results: Multivariate Logistic regression analysis showed that: the age(OR 1.7,95 % CI 1.1-5.4), weight gained (OR 1.8,95 % CI 1.1-6.6), pre-pregnancy BMI(OR 2.0,95 % CI 1.05-5.3), more than 2 times of abortion(OR 3.5,95 % CI 2.7-21.4), a family history of diabetes(OR 2.6,95 % CI 2.0-14.9), hyperhemoglobinemia(OR2.7,95 % CI 1.7-7.7), and sweet tooth(OR 5.0,95 % CI 3.2-15.6) were the independent influencing factors for GDM (P＜0.05), whereas exercise more than 1 hours daily(OR 4.5,95 % CI 2.1-14.7) was a protective factor (P＜0.05). The proportions of cesarean section,premature birth,PIH,macrosomia and neonatal transfer to pediatrics in GDM-group were higher than those in healthy group(χ²_{cesarean section}=4.010,P＜0.05;χ²_{premature birth}=5.4351,P＜0.05;χ²_PIH=10.276,P＜0.01;χ²_Macrosomia=4.280,P＜0.05;χ²_{neonatal transfer to pediatrics}=12.041,P＜0.01).Conclusion: The morbidity of GDM is influenced by various factors, and can result in varied bad pregnancy outcomes. Prevention and intervention for GDM should be intensified in obstetrics.

Objective: to discuss the clinical features of rheumatoid arthritis (RA) in patients of different gender.Methods: 1 248 patients who were diagnosed with RA from July 2006 to January 2015 were collected and divided into Group Male and Group Female, with the general situation, laboratory examination and the involved heart learned.Results: The incidence age of the male patients were older than that of the female patients (P=0.016), there being no statistical significance (P＞0.05) . There were 54 cases of joint deformities, 117 cases of involved knee joints, 51 cases of dry mouths, 28 cases of dry eyes, 11 cases of combined high blood pressure and 17 cases of osteoporosis among male patients while there were 126 cases, 202 cases, 123 cases, 84 cases, 52 cases and 43 cases respectively in female patients , the difference being significant (P＜0.05). There were 59 cases of positive ANA , 34 cases of elevated platelets, 32 cases of reduced hemoglobin, 117case of abnormal ESR , 14 cases of abnormal creatinine abnormalities in male patients while there were 125 cases, 71 cases, 71 cases, 202 cases and 6 cases respectively in female patients , the significance being different (P＜0.05). There were no difference in terms of CRP, hemoglobin, white blood cells, positive anti-CCP and positive AKA between men and women (P＞0.05).Conclusion: The elderly men were susceptible to RA, while elderly women were susceptible to joint deformities, knee joint involvement,dry mouths, dry eyes, combined high blood pressure and combined osteoporosis. There were more ANA positive rates, increased platelets, hemoglobin and increased ESR in female patients than in male patients. There was more elevated serum creatinine in men than in women.

Objective: To explore the influence of comprehensive nursing intervention on the quality of life of patients with acute myelitis.Methods: A total of 64 patients with acute myelitis were chosen and randomly divided into the control group (n=30) and the observation group (n=34). The control group was given the routine diet and medication while the observation group was given comprehensive nursing of psychology, diet, defecation, complications and health rehabilitation , with the quality of life and nursing satisfaction compared between the two groups.Results: After the intervention, the total quality of life score and activity of daily living scale (ADL) score in the control group [(71.26±4.35), (56.37±4.31)] were significantly lower than those in the observation group [(83.49±4.60), (64.35±4.26)]; the nursing satisfaction rate of the control group (80.0%) was significantly lower than that of the observation group(χ²=7.503,P=0.006).Conclusion: The application of comprehensive nursing in patients with acute myelitis can significantly improve the quality of life and the nursing satisfaction rate, worthy of clinical promotion

Objective: To explore the influence of individualized pain care on pain and satisfaction in patients after total knee replacement.Methods: 160 cases of patients after total knee replacement from August 2016 to April 2017 were selected and divided into observation group and control group according to the different nursing methods (n=80). The control group was given routine nursing after operation, and the observation group was given individualized pain care on the basis of the control group. The pain score and nursing satisfaction of the two groups were compared.Results: The degree of pain in the observation group was better than that in the control group (P＜0.05). After nursing, the satisfaction degree (151.60±23.48) in the observation group was higher than that in the control group (127.92±20.83) (P＜0.05).Conclusion: Individualized pain care can reduce the pain level after total knee replacement and improve the patients' satisfaction.

Objective: To study the effect of applying hydrocolloid dressing joint colostomy products to the protection of surrounding skin in intestinal fistula patients.Methods: 50 cases of patients with intestinal fistula hospitalized in gastrointestinal surgery from January 2014 to October 2016 were selected and randomly divided into experimental group and control group, 25 cases in each group. The experimental group was treated with hydrocolloid dressing joint colostomy products, while the control group was treated with traditional continuous washing plus pressure suction and zinc oxide coating to protect the skin.Results: In terms of objective indicators, the dermatitis incidence and severity of the fistula surrounding skin in experimental group were significantly lower than those in control group (P＜0.05); the average daily dressing change was significantly less than that in control group (P＜0.05). The subjective assessment of indicators in the Nottingham health scale (NHP) in experimental group was superior to that in control group (P＜0.05).Conclusion: Hydrocolloid dressings joint colostomy products can protect fistula surrounding skin, effectively prevent pollution of liquid leakage to abdominal incision and stimulation of liquid leakage to the surrounding skin, accelerate the fistula healing, ease the family economic burden, and at the same time reduce the workload of medical staff, which is worthy of promotion.

Objective: To study the effect of early nutritional nursing models on the nutritional index and immune function of coma patients with brain injury.Methods: 40 cases of coma patients with traumatic brain injury from September 2015 to October 2016 were selected and randomly divided into control group (early parenteral nutrition support nursing) and observation group (early enteral nutrition support nursing), 20 cases in each group. The nutritional and immune function indexes were compared in the two groups.Results: The serum albumin, prealbumin , and hemoglobin values on the 7d after nutritional support in observation group were higher than those in control group (P＜0.05); Before the nutritional support, there were no statistic difference of immune function in the two groups (P＞0.05). On the 7d after nutritional support, the values of IgG, IgA and CD⁺₄ /CD⁺₈ were higher than those in control group (P＜0.05); there was no statistic difference of CD⁺₄ in the two groups (P＞0.05).Conclusion: Early enteral nutrition support nursing can improve the nutritional status and immune function of coma patients after traumatic brain injury, which is worthy of promotion.

Objective: To explore the application effect of holistic nursing and foreseeable nursing in the treatment of traumatic orthopedics.Methods: The control group was treated with holistic nursing, while the observation group was treated with foreseeable nursing. The therapeutic effect, occurrence rate of adverse reaction and satisfaction of nursing were compared in the two groups.Results: The excellence rate of therapeutic effect in the observation group was 97.50 % (78/80), which was higher than that in the control group (86.25 %, 69/80)(χ²=7.895,P=0.005). The occurrence rate of adverse reaction in the observation group was 5.00 % (4/80), which was higher than that in the control group (13.75 %, 11/80)(χ²=4.711,P=0.030). The satisfaction degree of the patients in the observation group (87.50 %) was higher than that in the control group (73.75 %)(χ²=5.538,P=0.019).Conclusion: The foreseeable nursing services in the treatment of traumatic orthopedic treatment can promote the therapeutic effects, reduce the occurrence of adverse reaction and increase the nursing satisfaction. It is worthy of clinical promotion.

Objective: To investigate the clinical significance of detection of tumor-associated antigen by cobas 601 full automatic electrochemiluminescence immunoassay analysis system.Methods: The cobas601 full automatic electrochemiluminescence immunoassay system was adopted to detect the tumor-associated antigen in 2000 cases of patients.Results: The abnormal results detection rates of serum CEA、AFP、PSA、CA₁₅₃、CA₁₂₅ and CA₁₉₉ were 33.3 % (150/450), 5.0 % (20/400), 30.6 % (94/307), 21.0 % (110/525), 16.1 % (25/155) and 13.5 % (22/163) respectively.Conclusion: The cobas601 full automatic electrochemiluminescence immunoassay system can be used to detect CEA、AFP、PSA、CA₁₅₃、CA₁₂₅ and CA₁₉₉ an, and has clinical significance in the auxiliary diagnosis of colon cancer and primary hepatic carcinoma.

Objective: To study the clinical effect of pramipexole hydrochloride combined with benserazide hydrochloride on Parkinson disease.Methods: 160 cases of patients with Parkinson disease treated in the hospital from January 2012 to December 2016 were randomly divided into observation group and control group (n=80). The control group was treated with benserazide hydrochloride. The observation group was treated with pramipexole hydrochloride combined with benserazide hydrochloride. The motor function, the UPDRS score before and after treatment, and the incidence of adverse reactions such as nausea, vomiting, switching, psychiatric symptoms and so on were compared between the two groups.Results: The effective rate in the observation group was 95.00 %, which was significantly higher than that in the control group (83.75 %) (P＜0.05). The UPDRS scores of the two groups significantly decreased (P＜0.05) and the scores in the observation group was significantly lower than those in the control group (P＜0.05). There was no significant difference in the incidence of adverse reactions such as nausea, vomiting, switching phenomenon and psychiatric symptoms in the two groups (P＞0.05).Conclusion: Pramipexole hydrochloride combined with benserazide hydrochloride is safe and effective in the treatment of Parkinson disease, which can significantly improve the motor function of patients. It is worthy of promotion.

The teaching of cardiovascular surgery has always been difficult in the surgery teaching. The teaching time was short, but the content was complicated and multifarious. Furthermore, there was no clinical practice of cardiovascular surgery in Capital Medical University and thus the students paid less attention to it. The multimedia and image data are fully used and various teaching methods are combined for students to understand the overall perspective quickly, master the key diseases and remedy the shortcoming of no clinical practice.

Objective: To explore the incidence of liver damage and the factors that cause liver damage in the population with occupational diseases, and to provide reasonable suggestions for the prevention of liver damage.Methods: 30000 cases of patients were randomly selected from the occupational disease group of Boluo County Center for Disease Control and Prevention (CDC) from January 2013 to August 2016 as the observation group. 30 000 cases were selected from non-occupational disease group at the same time. The incidence of liver damage in the two groups was statistically analyzed, and the incidence of liver damage was calculated according to the length of service in the observation group.Results: The incidences of fatty liver, abnormal liver function, excessive arsenic in blood and excessive blood lead in the observation group were higher than those in the control group (P＜0.05).With the extension of service length, the incidence of liver damages showed an upward trend in the observation group (P＜0.05).Conclusion: The incidence of liver damage in occupational disease group is high, and the length of service is an important factor affecting the liver damage. The working environment of occupational groups should be improved under the consideration of the influencing factors, and self-protection should be strengthened to reduce the adverse effects of various toxic substances in occupational diseases to protect people's occupational life and health.

Objective: To explore the effect of multidisciplinary nursing on pulmonary rehabilitation of lung cancer patients after lobectomy.Methods: 80 lung cancer patients who underwent lobectomy from March 2016 to February 2017 were chosen and randomly divided into the observation group and the control group, 40 patients in each group. The control group was treated with routine specialist care while the observation group was treated with multidisciplinary care, with lung function indexes, 6 minutes walk test (6MWT), the postoperative pulmonary complication rate and postoperative hospitalization time compared.Results: The postoperative respiratory rate was significantly lower in the observation group than that in the control group(t=2.341, P=0.015); maximal voluntary ventilation (MVV), forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC and 6MWT after operation in the observation group were significantly higher than those in the control group (P＜0.05). The incidence rates of pulmonary infection, atelectasis and respiratory failure were lower and the average hospital stay was shorter in the observation group than those in the control group (P＜0.05).Conclusion: Multidisciplinary care can improve lung rehabilitation after lobectomy quickly and effectively, reduce the incidence of pulmonary complications, shorten the hospital stay and improve the quality of care.

Objective: To discuss the value and advantage of head and neck CT angiography (CTA) examination by spiral CT in the diagnosis of cerebral infarction.Methods: 160 cases of patients with cerebral infarction from February 2015 to February 2017 treated in the hospital were selected as the research objects. All patients were given head and neck CTA examination by spiral CT and the diagnostic effects were recorded.Results: The CBF, TTP, CBV and MTT values in the injured side were (24.38±6.42)mL/(100g·min), (3.58±1.23)mL/100g, (8.11±2.67)s and (23.19±5.99)s respectively, which had significant difference from those in the healthy side (P＜0.05). Carotid plaques were detected in the 160 patients with CTA examination, including 40 cases of soft plaque, 60 cases of mixed plaque, and 60 cases of hard plaque.Conclusion: Head and neck CTA examination by spiral CT in the diagnosis of cerebral infarction has a good application value and can reflect the degree of disease and plaque nature. It is worthy of popularization and application.

Objective: To explore the effect of different anesthesia methods on heart rate and complication before and after intubation and extubation in pediatric laparoscopic surgery.Methods:85 cases of children undergoing laparoscopic surgery from September 2016 to January 2016 were selected as the subjects and, according to the different methods of anesthesia, divided into group A (laryngeal mask) and group B (sacral block compound laryngeal mask). The heart rate and the incidence of complications before and after intubation and extubation were compared.Results: The heart rate fluctuation at different time in group A was large while in group B was smooth; the heart rates at T1, T2 and T3 in group A were higher than those in group B (t=7.0509, 12.073, 13.3165, P=0.0000). The postoperative complications rate in group A was 18.60%, which was higher than that in group B (4.76 %) (χ²= 3.922, P=0.048 ).Conclusion: Sacral block compound laryngeal mask general anesthesia for pediatric laparoscopic surgery, with stable heart rate and low incidence of complications, can ensure the satisfactory effect and is worthy of popularization and application.

Objective: To investigate the effect of arthroscopic rotator cuff suture combined with manual loosening on postoperative shoulder joint mobility and quality of life in patients with rotator cuff tears and shoulder joint adhesion.Methods: 57 cases of patients with rotator cuff tears and shoulder joint adhesion in the hospital from January 2014 to May 2016 were selected. Arthroscopic rotator cuff suture and manual loosening were performed after admission and followed up for 6 months. The visual analogue scale (VAS) scores, shoulder flexion and abduction, lateral rotation, and quality of life (SF-36) scores were compared between the two groups at rest and after activity before and 6 months after the operation.Results: 6 months after operation, the VAS scores of patients at rest and after activity were lower than those in the control group (P＜0.05). The flexion, abduction and lateral rotation of the shoulder joint were greater than those before the treatment (P＜0.05). The scores of life quality (SF-36) were higher than those before treatment (P＜0.05).Conclusion: The arthroscopic rotator cuff suture combined with manual loosening in the treatment of patients with rotator cuff tears and shoulder joint adhesion can effectively relieve shoulder pain and improve shoulder mobility. It is beneficial to the improvement of the patients' quality of life.

Objective: To observe the clinical efficacy of paclitaxel combined with radiotherapy in the treatment of advanced breast cancer and evaluate the safety.Methods: 74 patients with advanced breast cancer were chosen and randomly divided into the observation group and the control group, 37 cases in each group. The observation group wastreated with paclitaxel chemotherapy combined with radiotherapywhile the control group was treated with radiotherapy treatment for a total of 2 courses of treatment, with the improvement of life quality, expression levels of the tissue in patients with Bax and p53 mRNA , clinical efficacy and incidence of adverse reactions compared.Results: After treatment, the total efficiency rate of the observation group is higher than that of the control group (χ²=7.929, P=0.005); the improvement rate of life quality in the observation group (62.2 %) was higher than that of the control group (18.9 %) (χ²=14.352, P=0.000).Before treatment, there was no difference in the expression levels of Bax and p53 mRNA in breast tissue of the two groups (P＞0.05). After treatment, the two expression levels were increased (P＜0.05), and the expression levels of Bax and p53 mRNA in the observation group were higher than those of the control group (P＜0.05); the incidence rates of adverse reaction in the observation group and the control group were 13.51% (5/ 37) and 16.22 % (6/37) respectively, there being no difference(χ²=0.107,P=0.743).Conclusion: Paclitaxel concurrent radiotherapy and chemotherapy can improve the therapeutic efficacy for patients with advanced breast cancer, improve the quality of life and the expression levels of Bax and p53 in breast tissueand have less adverse reactions, worthy of popularization and application.

Objective: To investigate the clinical effects of segmented sneak Milligan-Morgan operation and selective interrupted suture in the treatment of circular mixed hemorrhoids.Methods: A total of 100 patients with circular mixed hemorrhoids in the hospital were randomly divided into observation group and control group, 50 cases in each group. The observation group was treated by segmented sneak Milligan-Morgan operation and selective interrupted suture while the control group was treated by Milligan Morgan operation alone. The clinical efficacy was compared.Results: The degree of incision pain, complications incidence, hospitalization and wound healing time in the observation group were better than those in the control group (P＜0.05).Conclusion: The treatment of circular mixed hemorrhoids with segmented sneak Milligan-Morgan operation and selective interrupted suture can shorten the hospitalization time, reduce postoperative pain and promote recovery.