25 December 2025, Volume 41 Issue 12
    

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  • ZHANG Yu, LIU Jinlong, ZHAO Jianjun, ZHAO Ying, WANG Shupeng, WANG Yanting, WEI Yiyi, YANG Yonghua, WANG Jiale, ZHANG Yujie, BAI Huimin
    Journal of Baotou Medical College. 2025, 41(12): 1-5. https://doi.org/10.16833/j.cnki.jbmc.2025.12.001
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    Objective: To analyze the epidemiological characteristics of hepatitis E virus (HEV) infection among aquaculture population in Baotou City, and to evaluate the infection rate of different age groups, so as to provide data support for the prevention and control of hepatitis E in the aquaculture population. Methods: Blood samples of aquaculture population (pigs, cattle, sheep) in Baotou City from July 2023 to July 2024 were collected, and HEV-IgG antibodies in serum were detected by ELISA. Grouped according to the age, and the positive rate of infection in each age group was counted. Results: A total of 679 samples were collected. The positive infection rates of each age group were as follows: the group from 0 to≤20 years was 3.23%,>20 to≤30 years was 10.87%,>30 to≤40 years was 14.93%, >40 to≤50 years was 41.28%, >50 to≤60 years was 50.00%,>60 to≤70 years was 34.52%, >70 to≤80 years was 68.57%, >80 to≤90 years was 60.00%. The results of the chi-square test showed that the positive infection rates of the groups >30 to≤40 years old,>40 to≤50 years old, >50 to≤60 years,>70 to≤80 years, and>80 years to≤90 years were significantly different compared with those of other age groups (P<0.001). Conclusion: The positive rate of HEV infection in Baotou breeding population is higher, especially in the population over 40 years old, indicating that the aquaculture population may face a higher risk of HEV exposure, and it is necessary to strengthen the prevention and control of this virus.
  • YU Guangjia, GUO Kai, HU Yueyang, LYU Gang, AI Rong, HE Jinxin, WANG Qi, KANG Ningshuo, FAN Rong, GUO Yufeng, BAI Gang, JIA Yueqi
    Journal of Baotou Medical College. 2025, 41(12): 6-9. https://doi.org/10.16833/j.cnki.jbmc.2025.12.002
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    Objective: To explore the correlation between problematic drinking and psychological well-being among occupational populations. Methods: A total of 1,758 employees were recruited from 8 workplaces in Baotou City. General demographic characteristics, the independent variable of problematic drinking (assessed by the CAGE questionnaire), and the dependent variable of well-being (assessed by the 5-item World Health Organization Well-Being Index, WHO-5) were collected. Logistic regression analysis was used to analyze the association between problematic drinking and psychological well-being. Results: The detection rate of problematic drinking among the participants was 20.25%. The mean psychological well-being score was 14.42±6.81 in problematic drinkers, versus 15.09±6.57 in non-problematic drinkers. Psychological well-being scores were significantly lower in employees with problematic drinking than in non-drinkers (15.41±6.57, P=0.007). Additionally, the score of problematic drinking was negatively correlated with psychological well-being score (β=-0.331,OR 95%CI:0.536-0.962). Conclusion: Problematic drinking was negatively correlated with psychological well-being among occupational populations: the more severe the problematic drinking, the lower the psychological well-being.
  • LIN Jiajing, QING Geer, JIAO Dingyi, XIE Wei, XIE Yabin, XU Wenqiang, SHI Rui, JIA Xiao'e, JIANG Shuyuan, LIU Xiaolei, BAO Mulan, BADE Rengui
    Journal of Baotou Medical College. 2025, 41(12): 10-15. https://doi.org/10.16833/j.cnki.jbmc.2025.12.003
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    Objective: To study the effect of ciliary neurotrophic factor (CNTF) on the apoptosis of hippocampal neurons (HT22) in oxygen-glucose deprivation (OGD) model mice. Methods: HT22 cells, which were replaced with sugar-free medium, were cultured in a hypoxic incubator for 6 h, and then transferred to a normoxic incubator for reoxygenation for 18 h. The morphological changes of cells were observed, the expression of apoptosis-related factor protein was detected, and the expression of apoptosis-related factor mRNA was detected. The plasmids (sh-nc, sh-cntf, oe-cntf) and inhibitors (sh-akt) were transfected into HT22 cells, and the sugar-free medium was replaced and cultured in the hypoxic incubator for 6 h, then transferred to a normal-oxygen incubator for 18h. The expression of HT22 apoptosis-related factors and AKT/STAT3 protein in each group were detected. Results: Compared with the normal group, the apoptosis level of the OGD treatment group was increased and the anti-apoptosis ability was decreased. Under the microscope, the cell body vacuoles of the OGD group were significantly increased. Compared with the normal group, the apoptosis level of the OGD group and the sh-nc+OGD group was significantly increased, and there was no significant difference between the two groups. The apoptosis level of sh-cntf group was further increased, but the apoptosis level of oe-cntf group was significantly decreased. Compared with the normal group, the apoptosis level in the AKT knockdown group (sh-akt) and the co-knockdown group with AKT and CNTF (sh-akt+cntf) was significantly increased, and the apoptosis level in the sh-akt+cntf group was more significantly increased. Apoptosis was inhibited after AKT knockdown and CNTF overexpression (sh-akt+oecntf). Conclusion: CNTF plays a protective role by up-regulating AKT/STAT3 signaling pathway and activating phosphorylation at phosphoric acid site 705 in STAT3, thereby inhibiting the apoptosis of neuronal cells after OGD.
  • LI Shuzhen, SUN Xinyu, CHANG Haowen, XIE Wei, LIU You
    Journal of Baotou Medical College. 2025, 41(12): 16-20. https://doi.org/10.16833/j.cnki.jbmc.2025.12.004
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    Objective: To explore the expression and role of brain-derived neurotrophic factor (BDNF) and its signaling pathway in hippocampal brain region of hypoxic preconditioning-treated mouse epilepsy model. Methods: ICR male mice were randomly divided into three groups: normal group (Control), epilepsy group (Epilepsy), hypoxic preconditioning treatment epilepsy group (HPC1+E). The mice were injected with pentylenetetrazol to construct an acute epilepsy-like behavior model. The epileptic behavior of mice was observed, the related biochemical indexes in the hippocampus of mice were detected, and the expression of BDNF and tropomyosin receptor kinase B (TrkB) protein in mice was detected. Results: Compared with the Control group, the five-level seizure rate and seizure level of the Epilepsy group were significantly increased (P<0.05), and the five-level seizure rate and seizure level of the HPC1+E group were significantly decreased. The protein expression of BDNF and P-TrkB in the Epilepsy group was significantly decreased (P<0.05), and the protein expression of BDNF and P-TrkB in the HPC1+E group was significantly increased. Conclusion: Hypoxic preconditioning treatment can significantly alleviate epilepsy-like behavior, which may play a role by up-regulating BDNF expression and activating its downstream signaling pathway.
  • LI Wenxin, LIU Xingling, LV Jun, MA Baohui, WANG Lijun, QI Ruifang
    Journal of Baotou Medical College. 2025, 41(12): 21-25. https://doi.org/10.16833/j.cnki.jbmc.2025.12.005
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    Objective: Investigating whether tuberous sclerosis complex 1 (TSC1) modulates autophagy via the mammalian target of rapamycin (mTOR) pathway under hypoxic preconditioning (HPC) conditions to alleviate neuronal injury. Methods: Hypoxia and HPC models were established using HT22 hippocampal neuronal cells. Apoptosis was quantified by flow cytometry. Genetic interventions (knockout/overexpression) targeting TSC1 were performed, followed by Western blot analysis of mTOR and LC3 autophagy marker (LC3Ⅱ/LC3I ratio) expression. Results: Compared to the hypoxia group, HPC significantly reduced neuronal apoptosis in HT22 cells (P<0.05). TSC1 overexpression during hypoxia suppressed mTOR expression and concurrently decreased LC3Ⅱ/LC3I levels (P<0.05). Conversely, TSC1 knockout under HPC elevated mTOR protein levels and increased the LC3Ⅱ/LC3I ratio (P<0.05). Conclusion: TSC1 exerts neuroprotective effects under HPC likely through mTOR pathway-dependent regulation of autophagy.
  • WANG Zhiguang, YAN Lei, SHAO Guo, LIU You, JIANG Shuyuan
    Journal of Baotou Medical College. 2025, 41(12): 26-32. https://doi.org/10.16833/j.cnki.jbmc.2025.12.006
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    Objective: To investigate the mechanism of remote ischemic preconditioning in achieving neuroprotection by regulating synaptic plasticity proteins via the NR2B subunit of the NMDA receptor. Methods: In animal experiments, 30 male mice were randomly divided into four groups: sham operation group (SHAM group), middle cerebral artery occlusion group (MCAO/R group), middle cerebral artery occlusion plus remote ischemic preconditioning group (MCAO/R+RIPC group), middle cerebral artery occlusion plus remote ischemic preconditioning plus exosome inhibitor group (MCAO/R+RIPC+GW4869 group). In cell experiments, mouse hippocampal neurons were divided into three groups: control group C (Control) after oxygen-glucose deprivation and reperfusion (OGD/R ), NC group treated with exosomes from normal mice and treated with oxygen-glucose deprivation and reperfusion (OGD/R), RIPC group treated with exosomes from RIPC mice and treated with oxygen-glucose deprivation and reperfusion (OGD/R). The expression of synapse-related genes (GAP-43, SYN, PSD95) and NR2B was detected by real-time fluorescence quantitative PCR and Western blot, respectively. Results: Animal experiment: Compared with SHAM group, the expression of GAP43, SYN and PSD95 in MCAO/R group was decreased (P<0.05), and the expression of NR2B was increased (P<0.05). Compared with the MCAO/R group, the expression of synaptic-related proteins was increased after RIPC treatment (P<0.05), and the expression of NR2B was decreased (P<0.05). Compared with the MCAO/R+RIPC group, the expression of synaptic-related proteins was decreased after the addition of exosome inhibitors (P<0.05), and the expression of NR2B was increased (P<0.05). Cell experiments: Compared with group C, the levels of synapse-related genes (GAP43, SYN and PSD95) in RIPC group were increased (P<0.05), and the expression of NR2B was decreased (P<0.05). Conclusion: Remote ischemic preconditioning may enhance synaptic function through NMDARs, thereby alleviating cognitive dysfunction and ischemic brain injury.
  • FENG Zilong, BAO Jianmin, SHAO Guo, ZHAO Zhijun, ZHANG Chunyang, SUN Zhigang
    Journal of Baotou Medical College. 2025, 41(12): 33-39. https://doi.org/10.16833/j.cnki.jbmc.2025.12.007
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    Objective: To explore the mechanism of concentrated growth factor (CGF) in the autologous repair of skull defect. Methods: Without damaging the dura mater, a circular defect with a diameter of 3 mm was made in the left parietal bone of 2-week-old rats. After removal of the bone flap, they were divided into the Control group and the CGF group. Subsequently, 5 μg of hydrogel and CGF gel were respectively added to the skull defect sites of the two groups, and the skin was sutured. The experiment lasted for a total of 4 weeks. Six rats from each group were sacrificed weekly to measure the remaining area of the defect and other physiological indexes. After 4 weeks, the remaining 16 rats in each group were sacrificed to obtain samplesfor determination of the expression levels of SMAD1, RUNX2, and OSX in the skull and dura mater at the defect site by Western-blot and Real-time qPCR. Results: At the end of the experiment, the defect area of the rats in the CGF group was significantly smaller than that in the Control group, with statistical significance (P<0.001). The results of HE staining showed that the number of new bone trabeculae and inflammatory factors in the defect area of the CGF group was significantly different from that of the Control group. Western-blot and Real-time qPCR showed that the expression levels of SMAD1, RUNX2, and OSX in the skull and dura mater of the CGF group were significantly higher than those of the Control group, with statistical significance (P<0.001). Conclusion: Under the effect of CGF, the speed of autologous repair of skull defect is significantly accelerated, and the mRNA and protein expression of SMAD1, RUNX2 and OSX in skull and dura mater is enhanced. The dura mater may play an important role in promoting the process of autologous repair of skull defects through the SMAD1 / RUNX2 / OSX pathway.
  • YOU Yuan, JIANG Shuyuan, ZHU Hongwei, WANG Peng, LI Bifei, XIE Wei, JIA Xiaoe, SHAO Guo, LIU You
    Journal of Baotou Medical College. 2025, 41(12): 40-45. https://doi.org/10.16833/j.cnki.jbmc.2025.12.008
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    Objective: To investigate the effects and underlying molecular mechanisms of plasma-derived exosomes from patients with type 2 diabetes mellitus (T2DM) on SH-SY5Y neuronal cells under an oxygen-glucose deprivation (OGD) model. Methods: Plasma exosomes were isolated from healthy individuals and T2DM patients using differential ultracentrifugation. Exosomal markers CD9 and HSP70 were identified via Western blot, and particle size distribution was analyzed using a Zetasizer. The OGD model was established by subjecting cells to glucose-free, low-oxygen conditions for 6 hours followed by 24 hours of reoxygenation. SH-SY5Y cells were divided into six groups: control (C), OGD (G), and exosome-treated groups (C-EXO, C-EXO-T2DM, G-EXO, G-EXO-T2DM). Cell proliferation was assessed using the CCK8 assay. Apoptosis levels were evaluated via flow cytometry and live-cell imaging. Expression of apoptosis-related proteins (spectrin and Bcl-2) was analyzed by Western blot. Results: Exosomal markers CD9 and HSP70 were positively expressed, and exosome diameters ranged from 30 to 150 nm. Co-culture with T2DM-derived plasma exosomes significantly reduced cell viability in the OGD group (P<0.05), with increased spectrin expression and decreased Bcl-2 expression. Flow cytometry revealed elevated early apoptosis rates induced by T2DM plasma exosomes. Conclusion: T2DM plasma exosomes aggravate neuronal apoptosis under OGD conditions by regulating the Bcl-2/spectrin pathway, suggesting a potential pathogenic role in diabetes-associated stroke.
  • WANG Menghan, WANG Mizhu
    Journal of Baotou Medical College. 2025, 41(12): 46-50. https://doi.org/10.16833/j.cnki.jbmc.2025.12.009
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    Objective: To investigate the expression of olfactory protein-like 2B (OLFML2B) in colon cancer tissues. Methods: The gene expression difference of OLFML2B in pan-cancer was analyzed by TCGA database. The expression levels of OLFML2B, phosphorylated protein kinase B (p-AKT), transcription factor MYB and cyclin D1 (CCND1) in cancer tissues and adjacent normal tissues of patients with colon cancer were detected by immunohistochemistry and Western blotting, and the potential links of these proteins in the development of colon cancer were analyzed. Results: In the pan-cancer study, the expression of OLFML2B was significantly different in various tumor tissues, and it was highly expressed in a variety of tumor tissues, such as colon cancer, lung adenocarcinoma, renal clear cell carcinoma, gastric adenocarcinoma, hepatocellular carcinoma, etc. (P<0.05). In TCGA-COAD paired samples, OLFNL2B was highly expressed in colon cancer. Immunohistochemistry and Western blot analysis showed that the expression levels of OLFML2B, p-AKT, MYB and CCND1 in colon cancer tissues were significantly higher than those in adjacent normal tissues (P<0.05). Spearman correlation analysis showed that OLFML2B was positively correlated with the expression of p-AKT, MYB and CCND1 in colon cancer (P<0.05). Conclusion: OLFML2B, p-AKT, MYB and CCND1 are highly expressed in colon cancer, which may promote the occurrence and development of cancer through interaction, and its mechanism may be related to phosphatidylinositol-3-hydroxykinase (PI3K/Akt) signaling pathway.
  • QIN Kai, MO Junyang, QIN Shuting, SONG Chang, QU Ning, CHEN Gang, PANG Yuyan
    Journal of Baotou Medical College. 2025, 41(12): 51-55. https://doi.org/10.16833/j.cnki.jbmc.2025.12.010
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    Objective: To investigate the expression and prognostic value of transmembrane protein 206 (TMEM206) in thyroid cancer (TC). Methods: Standardized mean difference combined with random effect model was used to analyze the difference of TMEM206 expression between TC and non-cancerous thyroid tissues in multi-center samples, and Kaplan-Meier method was used to evaluate its prognostic value. Results: The expression of TMEM206 mrna in TC tissues was higher than that in non-cancerous thyroid tissues (SMD=0.42, 95%CI: 0.08-0.77), and Egger and Begg tests showed no significant bias (P>0.05). The expression characteristics of TMEM206 mrna were evaluated by receiver operating characteristic curve, with a sensitivity of 0.57 (95%CI: 0.39-0.74) and a specificity of 0.84 (95%CI: 0.58-0.95), the positive likelihood ratio was 3.57 (95%CI: 1.36-9.38), and the negative likelihood ratio was 0.51 (95%CI: 0.36-0.72). At the protein level, the expression of TMEM206 in TC tissues was significantly higher than that in non-cancerous tissues (P<0.05). Conclusion: TMEM206 is highly expressed in TC, suggesting that it may be involved in the pathological process of TC, and its molecular mechanism needs to be clarified through functional experiments in the future.
  • DANG Wenqi, REN Limei, WU Jinbao, WANG Chi, SU Qihao
    Journal of Baotou Medical College. 2025, 41(12): 56-61. https://doi.org/10.16833/j.cnki.jbmc.2025.12.011
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    Objective: To investigated the expression of receptor-interacting protein kinase 3 (RIPK3) in gastric adenocarcinoma and precancerous tissues. Methods: The study focuses on 170 pathological samples of gastric adenocarcinoma and precancerous lesions collected from the Second Affiliated Hospital of Baotou Medical College from December 2022 to June 2024, pathological samples including 40 cases of chronic superficial gastritis, 40 cases of chronic atrophic gastritis with intestinal metaplasia, 40 cases of heterotrophic hyperplasia and 50 cases of gastric adenocarcinoma. To use immunohistochemistry to detect the expression of RIPK3. Meanwhile, 30 fresh tissue samples are collected to detect the expression of RIPK3 using Western blot. The relationship between RIPK3 expression and survival of gastric adenocarcinoma patients is analysed by Kaplan-Meier plotter, and the association between RIPK3 and the tumour microenvironment (TME) of gastric cancer is explored using TISCH database. Results: (1) Immunohistochemistry shows that the positive expression rate of RIPK3 in gastric adenocarcinoma is significantly lower than that in other groups (P<0.05) and correlated with the depth of tumour infiltration, TNM stage, vascular invasion and lymph node metastasis (P<0.05). (2) Western blot results shows that the expression of RIPK3 in chronic superficial gastritis, chronic atrophic gastritis with intestinal metaplasia and gastric adenocarcinoma gradually decreased (P<0.01). (3) Kaplan-Meier analysis shows that gastric adenocarcinoma patients with high RIPK3 expression has longer overall survival (OS) and progression-free survival (FP). (4) TME analysis reveals that RIPK3 expression is closely associated with intercellular stroma and mucus secretion. Conclusion: Low expression of RIPK3 is associated with gastric adenocarcinoma occurrence, infiltration, metastasis and poor prognosis.
  • HUANG Peining
    Journal of Baotou Medical College. 2025, 41(12): 62-67. https://doi.org/10.16833/j.cnki.jbmc.2025.12.012
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    Objective: To analyze the risk factors of postoperative infection after high intensity focused ultrasound (HIFU) in gynecology department, and to evaluate the effect of pelvic inflammatory disease treatment on postoperative infection after HIFU. Methods: A total of 100 female patients who underwent HIFU ablation in Jiangmen Xinhui District Maternal and Child Health Care Hospital from April 1, 2024 to January 31, 2025 were selected. Univariate analysis and Logistic regression analysis were used to identify the influencing factors of postoperative infection. Patients with postoperative infection after HIFU were divided into the observation group and the control group by random number table method. The observation group was treated with pelvic inflammatory disease treatment, and the control group was treated with prophylactic antibiotics. The clinical efficacy, laboratory indexes and disappearance time of clinical symptoms were compared between the two groups. Results: Postoperative infection occurred in 42 patients (42.00%) after HIFU. Univariate analysis showed that treatment time (>60 min), energy input (>200 kJ), and preoperative uterine cavity operations (electroresection, curettage) significantly affected the occurrence of postoperative infection after HIFU (P<0.05), while age and disease type had no significant effect (P>0.05). Logistic regression analysis indicated that treatment time, energy input, and preoperative uterine cavity operations (electroresection, curettage) were independent risk factors for postoperative infection after HIFU (P < 0.05). The total effective rate of clinical efficacy in the observation group was 95.24%, which was significantly higher than 71.43% in the control group (P<0.05). There was no significant difference in white blood cell (WBC), C-reactive protein (CRP), and procalcitonin (PCT) levels between the two groups before treatment (P>0.05). After 14 days of treatment, the levels of WBC, CRP, and PCT in the observation group were lower than those in the control group (P<0.05). The disappearance time of abdominal pain and the time for body temperature to return to normal in the observation group were shorter than those in the control group (P<0.05). Conclusion: Postoperative infection after HIFU is a major factor affecting the recovery of gynecological patients. Its occurrence is mainly related to treatment time >60 min, energy input >200 kJ, and preoperative uterine cavity operations (such as electroresection and curettage), while age and disease type have a relatively small impact. The pelvic inflammatory disease treatment regimen for postoperative infection after HIFU can significantly improve clinical efficacy, improve inflammatory indicators, and shorten the time for abdominal pain and body temperature to return to normal, providing new ideas for the prevention and treatment of postoperative infection after HIFU.
  • LI Jiamin, JI Xuemei
    Journal of Baotou Medical College. 2025, 41(12): 68-72. https://doi.org/10.16833/j.cnki.jbmc.2025.12.013
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    Objective: To investigate the value of CA125, PA, CHE and RDW in evaluating liver function in patients with liver cirrhosis. Methods: A total of 80 patients with liver cirrhosis who were first diagnosed and treated in the Department of Gastroenterology of Baotou Central Hospital from June 2023 to October 2024 were randomly selected. According to the period of liver cirrhosis, they were divided into compensatory group (25 patients) and decompensated group (55 patients). The serum samples of 100 patients with normal results were selected in the control group. The CA125, prealbumin (PA), cholinesterase (CHE) and red blood cell distribution width (RDW) were compared between the study group and the control group. The area under the ROC curve (AUC) was used to evaluate the value of single or combined detection of CA125, PA, CHE and RDW in evaluating liver function in patients with cirrhosis. Spearman correlation analysis was used to analyze the correlation between CA125, PA, CHE and RDW levels and disease severity. Results: The levels of serum CA125 and RDW in the study group were higher than those in the control group, while the levels of PA and CHE were lower than those in the control group, and the differences were statistically significant (P<0.05). ROC curve results showed that the AUC value of combined detection of serum CA125, PA, CHE and RDW was 0.96, which was higher than that of other single detections. Correlation analysis showed that the correlation between combined detection and disease severity was stronger (r=0.87) (P<0.05). Conclusion: There are significant differences in CA125, PA, CHE and RDW levels in patients with cirrhosis at different stages. Combined detection has a higher value in evaluating liver function in patients with cirrhosis.
  • HE Bingyang
    Journal of Baotou Medical College. 2025, 41(12): 73-77. https://doi.org/10.16833/j.cnki.jbmc.2025.12.014
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    Objective: This study aimed to investigate the clinical significance of neutrophil percentage-to-albumin ratio (NPAR) in evaluating degree of coronary artery lesion and predicting prognosis of patients with coronary heart disease (CHD). Methods: A case-control study was conducted, enrolling 112 CHD patients admitted to Zhengzhou Second People's Hospital (September 2020-October 2023) and 112 age-/gender-matched healthy controls. Participants were stratified into high (n=70) and low (n=42) severity subgroups based on Gensini scores. Clinical parameters were systematically collected, including demographic characteristics, laboratory biomarkers, and imaging data. Six-month readmission outcomes were tracked to establish prognostic subgroups. Spearman's correlation analysis assessed NPAR-Gensini score associations, while multivariate logistic regression models identified independent predictors of severe coronary lesions. Results: CHD patients exhibited significantly elevated NPAR levels compared to controls (P<0.05). Stratified analysis revealed higher NPAR values in the high Gensini score subgroup versus the low-score subgroup (P<0.05), and in readmission cases versus non-readmission cases (P<0.05). NPAR demonstrated a strong positive correlation with Gensini scores (r=0.611, (P<0.001). Multivariate analysis identified NPAR as an independent risk predictor for severe coronary lesions (OR=6.037, 95% CI: 3.527-9.724). Conclusion: Elevated NPAR levels are closely associated with advanced coronary atherosclerosis and adverse clinical outcomes in CHD patients. This biomarker shows promise as a cost-effective prognostic tool for risk stratification and readmission prediction in CHD management.
  • SUN Shuyan, PEI Hanjun, HUO Jingwei, SONG Jian, GAO Yuan
    Journal of Baotou Medical College. 2025, 41(12): 78-80. https://doi.org/10.16833/j.cnki.jbmc.2025.12.015
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    Coronary artery calcification (CAC) has a significant impact on interventional surgery, which may bring a series of challenges to the process and results of interventional surgery. Severe calcified plaques will increase the difficulty of surgery, prolong the operation time, and increase the probability of complications such as postoperative vascular injury, poor stent implantation and thrombosis. These complications may also lead to vascular restenosis or even re-occlusion, affecting the effect of surgery, and may require additional treatment. The traditional calcification treatment technology has certain limitations. While, Shockwave shock wave balloon is a kind of innovative vascular calcification treatment technology, which has the characteristics of low postoperative complications and good effect on moderate and severe deep calcification. It has become a new tool for interventional doctors to deal with CAC.
  • ZHANG Yu, WANG Xiulian, LI Shuixia, BAI Xuerui, LYU Yunrui, WANG Xueyuan, ZHAO Dong
    Journal of Baotou Medical College. 2025, 41(12): 81-84. https://doi.org/10.16833/j.cnki.jbmc.2025.12.016
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    On July 20, 2024, a case of imported severe malignant malaria was admitted to the Second Affiliated Hospital of Baotou Medical College. The patient returned from Sierra Leone on July 15, 2024. On July 20, he was admitted to the Department of Infectious Diseases of our hospital due to "darrhea for 2 days and fever for 1 day",accompanied by anemia, acute renal function injury, respiratory failure, shock, hyperlactacidemia, severe infection, liver dysfunction, jaundice, coagulation dysfunction and other serious complications, then transferred to the Department of Critical Care Medicine for treatment, and was given non-invasive ventilator respiratory support and bedside hemofiltration to stabilize the internal environment. At the same time, intramuscular injection of artemether injection combined with oral dihydroartemisinin and piperaquine phosphate tablets, supportive treatment, symptomatic treatment, intensive care and prevention of complications were given. One week later, the blood smear turned negative, and the function of each organ returned to normal. The patient was successfully rescued and discharged.
  • WEN Xinyan, HUANG Yangling, ZHANG Meng, LI Dongmei, WANG Zexi, JIANG Yuqing, PAN Yinuo, ZHANG Chi, MA Xiande
    Journal of Baotou Medical College. 2025, 41(12): 85-91. https://doi.org/10.16833/j.cnki.jbmc.2025.12.017
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  • BAI Xiaoxia, LI Shujun, CHEN Yongchong, ZHANG Chen, HAN Shuo
    Journal of Baotou Medical College. 2025, 41(12): 92-96. https://doi.org/10.16833/j.cnki.jbmc.2025.12.018
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