目的: 分析锥束CT(cone-beam computed tomography,CBCT)引导恶性肿瘤放射治疗的效果。方法: 选取2021年10月至2022年10月接受放射治疗的68例恶性肿瘤患者为研究对象,随机抽签法分为观察组与对照组,其中观察组34例患者行CBCT引导放射治疗,频率为1次/d,对照组34例患者同样接受CBCT引导放射治疗,频率为1次/3 d,对比分析CBCT引导方式临床成效情况。结果: 观察组x、y、z轴摆位误差及摆位外扩边界的绝对值均低于对照组(P＜0.05),观察组恶性肿瘤患者在大体肿瘤区、计划靶区的最大照射剂量、平均照射剂量均高于对照组(P＜0.05),观察组客观有效率高于对照组(P＜0.05),观察组各领域生存质量评分均高于对照组(P＜0.05)。结论: 利用CBCT在治疗前对恶性肿瘤患者进行扫描引导,可降低患者在放疗过程中的摆位误差,随着CBCT扫描频率的增加,更好地提升放疗的适应性与精确度,确保治疗成效,防止产生不适反应。

Objective: To analyze the effect of cone-beam computed tomography (CBCT) guided radiotherapy for malignant tumors. Methods: A total of 68 patients with malignant tumors who received radiotherapy from October 2021 to October 2022 were selected as the research objects. They were randomly divided into observation group and control group. Among them, 34 patients in the observation group received CBCT-guided radiotherapy, with a frequency of 1 time/d. 34 patients in the control group also received CBCT-guided radiotherapy, with a frequency of 1 time/3 d. The clinical effects of CBCT-guided methods were compared and analyzed. Results: The absolute values of x, y, z axis setup errors and setup expansion boundary in the observation group were lower than those in the control group (P＜0.05). The maximum irradiation dose and average irradiation dose of malignant tumor patients in the gross tumor area and planned target area in the observation group were higher than those in the control group (P＜0.05). The objective effective rate of the observation group was higher than that of the control group (P＜0.05). The quality of life scores in all fields of the observation group were higher than those of the control group (P＜0.05). Conclusion: For patients with malignant tumors, CBCT scanning and guidance before treatment can reduce the positioning error during radiotherapy. With the increase of CBCT scanning frequency, the adaptability and accuracy of radiotherapy can be better improved, the treatment effect can be ensured, and the discomfort reaction can be prevented.