目的: 探讨超声小探头在周围型肺癌患者中的临床应用。方法: 选择2021年1月-2022年12月中国科学院大学深圳医院(光明)接诊的周围型肺癌患者83例,患者均行小探头超声检查,以病理结果为金标准,根据有无淋巴结转移将患者分为转移组与非转移组,比较两组超声指标、彩色血流平均密度(mean color vessels eensity,MCVD)及病理微血管密度(microv essel density , MVD),并对MCVD及MVD进行相关性分析。根据TNM分期进行病情严重程度评估,比较两组患者MCVD及MVD,并对MCVD与TNM分期进行相关性分析。结果: 转移组患者低回声、回声不均匀、边界清晰、短径≥1.0 cm者占比分别为75.00%、85.71%、78.57%、71.43%,均高于非转移组的29.09%、40.00%、49.09%、38.18%(P＜0.05)。转移组患者MCVD及MVD水平均高于非转移组(P＜0.05)。Pearson相关性分析结果显示MCVD与MVD呈正相关关系(r=0.622,P＜0.05)。不同TNM分期患者MCVD与MVD差异均具有统计学意义,且均呈Ⅰ期＜Ⅱ期＜Ⅲ期(P＜0.05)。相关性分析结果显示MCVD与TNM分期呈正相关关系(r=0.817, P=0.013)。结论: 周围型肺癌患者出现淋巴结转移者低回声、回声不均匀、边界清晰、短径≥1.0 cm者占比更高,小探头超声MCVD与MVD及TNM分期均呈正相关关系。
Objective: To explore the clinical application of the ultrasound microprobe in patients with peripheral lung cancer.Methods: A study was conducted on 83 patients with peripheral lung cancer admitted to Shenzhen Hospital, University of Chinese Academy of Sciences from January 2021 to December 2022.All patients underwent small probe ultrasound examination. Based on the pathological results as the gold standard, the patients were divided into metastatic and non metastatic groups according to the presence or absence of lymph node metastasis. The ultrasound parameters, MCVD, and MVD in the two groups were compared, and the correlation between MCVD and MVD was analyzed. The severity of the condition was evaluated based on TNM staging, and the MCVD and MVD of each group of patients were compared, and the correlation between MCVD and TNM staging was analyzed. Results: The proportion of patients with low echo, uneven echo, clear boundary, and short diameter ≥ 1.0 cm in the metastatic group was 75.00%, 85.71%, 78.57%, and 71.43%, respectively, higher than 29.09%, 40.00%, 49.09%, and 38.18% in the non metastatic group (P＜0.05). The levels of MCVD and MVD in the metastatic group were higher than those in the non metastatic group (P＜0.05). Pearson correlation analysis showed a positive correlation between MCVD and MVD (r=0.622, P＜0.05). The differences in MCVD and MVD among patients with different TNM stages were statistically significant, and they were all in stages Ⅰ<Ⅱ<Ⅲ (P＜0.05). The correlation analysis results showed a positive correlation between MCVD and TNM staging (r=0.817, P=0.013).Conclusion: The proportion of patients with peripheral lung cancer who have lymph node metastasis is low echo, uneven echo, clear boundary, short diameter ≥1.0 cm were higher. Small probe ultrasound MCVD is positively correlated with MVD and TNM staging.
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