目的: 探讨视网膜血管管径的改变与脑白质疏松的关系。方法: 选择48例行颅脑核磁检查有脑白质疏松的患者和42例健康体检行颅脑核磁无脑白质疏松患者,采用Fazekas分级评价脑白质疏松分级,以视盘为中心拍摄双眼眼底相片,采用ImageJ 1.46软件测量距离视盘边缘1.5个视盘直径(DD)处的视网膜动脉和静脉颞上、颞下、鼻上、鼻下分支的血管外径算术平均值作为结果,比较伴有脑白质疏松患者的血管直径与不伴脑白质疏松患者的血管直径差异。结果: 脑白质结构疏松与视网膜中央动脉管径及动静脉管径之比呈负相关,并且与视网膜中央静脉直径呈正相关。结论: 视网膜中央血管管径与脑白质疏松有很大相关性,中央动脉血管管径越细、中央静脉管径越粗引起的视网膜血管病变越重,脑白质疏松的分级就越高。
Objective: To investigate the relationship between the change of retinal vascular diameter and the severity of leukoaraiosis.Methods: A total of 48 patients with leukoaraiosis and 42 healthy subjects without leukoaraiosis were selected.Fazekas classification was used to evaluate leukoaraiosis grading.Eyeground photographs were taken with optic disc as the center.ImageJ 1.46 software was used to measure the arithmetic measure the arithmetic mean of the external diameter of the retinal artery and the superior temporal, inferior temporal, superior nasal and inferior nasal branches of the vein at 1.5 optic disc diameters ( DD ) away from the edge of the optic disc.The differences in vascular diameter between patients with and without leukoaraiosis were compared.Results: The structure of white matter was negatively correlated with the ratio of central retinal artery diameter and arteriovenous diameter, and positively correlated with central retinal vein diameter.Conclusion: The central vascular diameter of retina is correlated with white matter thinning,The narrower the arterial vessel diameter and the wider the central venous vessel diameter, the more severe the retinal vasculopathy and the higher the grade of white matter loosening.
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