目的: 探讨Cobas 601型全自动电化学发光免疫分析系统检测肿瘤相关抗原结果的临床意义。方法: 利用Cobas 601型全自动电化学发光免疫分析系统,对2 000例患者进行肿瘤相关抗原检测。结果: 患者的血清CEA、AFP、PSA、CA153、CA125以及CA199水平异常结果检出率分别为33.3 %(150/450)、5.0 %(20/400)、30.6 %(94/307)、21.0(110/525)、16.1(25/155)以及13.5(22/163)。结论: Cobas 601型全自动电化学发光免疫分析系统用于检测CEA、AFP、CA125、CA153、CA199、PSA等肿瘤相关抗原,对于辅助诊断结肠癌、原发性肝癌等疾病,具有一定的临床意义。
Objective: To investigate the clinical significance of detection of tumor-associated antigen by cobas 601 full automatic electrochemiluminescence immunoassay analysis system.Methods: The cobas601 full automatic electrochemiluminescence immunoassay system was adopted to detect the tumor-associated antigen in 2000 cases of patients.Results: The abnormal results detection rates of serum CEA、AFP、PSA、CA153、CA125 and CA199 were 33.3 % (150/450), 5.0 % (20/400), 30.6 % (94/307), 21.0 % (110/525), 16.1 % (25/155) and 13.5 % (22/163) respectively.Conclusion: The cobas601 full automatic electrochemiluminescence immunoassay system can be used to detect CEA、AFP、PSA、CA153、CA125 and CA199 an, and has clinical significance in the auxiliary diagnosis of colon cancer and primary hepatic carcinoma.
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