Objective: To investigate the correlation between mild gastroenteritis with benign infantile convulsions (BICE) and serum iron, zinc, calcium and interleukin-6 (IL-6) levels in children, and to provide valuable reference information for further understanding the pathogenesis of BICE and optimizing its clinical diagnosis and treatment strategies. Methods: Forty children with BICE admitted to Baotou Fourth Hospital from October 2023 to October 2024 were selected as the BICE group, and 40 children with mild gastroenteritis admitted to the hospital during the same period were selected as the simple gastroenteritis group (control group). The expression levels of serum iron, zinc, calcium and IL-6 were compared between the two groups, and the correlation between the frequency and duration of convulsions in the BICE group and the levels of serum iron, zinc, calcium and IL-6 was analyzed. Results: The levels of serum iron, zinc and calcium in BICE group were lower than those in simple gastroenteritis group (all P＜0.05), while the level of serum IL-6 was higher than that in simple gastroenteritis group (P＜0.05). The levels of serum iron, zinc and calcium in children with seizure frequency ≥2 times and duration ≥5 min were lower than those in children with seizure frequency ＜2 times and duration ＜5 min (all P＜0.05), while the level of serum IL-6 was higher than that in children with seizure frequency ＜2 times and duration ＜5min (all P＜0.05). Spearman correlation analysis showed that the frequency and duration of seizures were negatively correlated with serum iron, zinc and calcium levels (all P＜0.05), and positively correlated with serum IL-6 level (all P＜0.05). Conclusion: The decrease of serum iron, zinc and calcium levels and the increase of IL-6 level are closely related to the occurrence of BICE.
GAO Yanping
,
QU Yanjie
. Correlation analysis of serum iron, zinc, calcium and IL-6 levels with mild gastroenteritis and benign convulsion in infants[J]. Journal of Baotou Medical College, 2026
, 42(3)
: 69
-73
.
DOI: 10.16833/j.cnki.jbmc.2026.03.014
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