Objective: To optimize and improve the quality standards of the Mongolian medicine Bengbare-7 flavor pills. Methods: Microscopic identification was carried out for four medicinal materials including Cinnamomi Cortex, Kaempferiae Rhizoma, Aucklandiae Radix and Lycii Fructus in Mongolian medicine Bengbare-7 flavor pills. Thin layer chromatography (TLC) method was used for the qualitative identification of Lycii Fructus, Aucklandiae Radix and Cinnamomi Cortex. High performance liquid chromatography (HPLC) method was adopted to determine the content of cinnamaldehyde, the main component in Cinnamomi Cortex. The mobile phase was acetonitrile-water (34∶66), the column temperature was 25 ℃, the detection wavelength was 290 nm, and the flow rate was 1.0 mL/min. Results: The powder characteristics of Cinnamomi Cortex, Kaempferiae Rhizoma, Aucklandiae Radix and Lycii Fructus had been distinct in the microscopic identification of Bengbare-7 flavor pills. TLC detection showed that the test sample and the reference substance showed characteristic spots of the same color at the same chromatographic position, and the negative control sample did not show speckle interference. with good specificity. The peak area of cinnamaldehyde had a good linear relationship in the concentration range of 7.38-21.95 μg/mL, and the regression equation was y=0.483 9x-0.454 6 ( R2=0.999 1), the average recovery was 101.4%, 100.4%, 102.1%, RSD was 0.84%, 0.35%, 0.44%. Conclusion: The microscopic identification, thin layer chromatography identification and content determination method of Mongolian medicine Bengbare-7 flavor pills constructed in this study have been verified to have accuracy, high sensitivity, good repeatability and precision, and excellent specificity, which can effectively help the improvement and optimization of the quality standard of Mongolian medicine preparation.
ZHANG Yuqing
,
GUO Ye
,
GUO Jingjing
,
YANG Yufei
,
ZHANG Qirui
,
AN Ming
. Optimization and improvement of quality standards for Bengbare-7 flavor pills[J]. Journal of Baotou Medical College, 2026
, 42(1)
: 22
-27
.
DOI: 10.16833/j.cnki.jbmc.2026.01.005
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