Objective: To analyze the composition and distribution characteristics of renal pathological disease spectrum in Inner Mongolia Autonomous Region in recent 20 years. Methods: The clinicopathological data of patients who underwent renal biopsy in the First Affiliated Hospital of Baotou Medical College of Inner Mongolia University of Science and Technology from 2004 to 2023 were collected, and the composition, proportion, change trend and clinical characteristics of renal biopsy pathological types were analyzed. Results: (1)A total of 2 765 renal biopsy cases were included, including 1 477 males (53.4%) and 1 288 females (46.6%).The average age was (45.1±15.7) years old, and the average age increased significantly. (2) The most common primary glomerular disease was membranous nephropathy (31.9%, 881 cases), followed by IgA nephropathy (25.1%, 695 cases) and minimal change nephropathy (10.7%, 296 cases), while the most common secondary glomerular disease was lupus nephritis (4.9%, 134 cases), followed by diabetic nephropathy (3.0%) and purpuric nephritis (2.8%). (3)The proportion of membranous nephropathy and diabetic nephropathy increased significantly in the same period (P＜0.05),while the proportion of IgA nephropathy decreased significantly in the same period (P=0.043), and the proportion of IgA nephropathy in the same period was lower than that of membranous nephropathy after 2014. Conclusion: In the past 20 years, the pathological spectrum of renal biopsy in Inner Mongolia has changed significantly. Since 2014, membranous nephropathy has surpassed IgAN as the most common primary glomerular disease. In addition, diabetic nephropathy is the secondary glomerular disease with the largest growth rate.
YU Yuexin
,
QIN Zirui
,
LYU Li
,
WANG Caili
. The 20-year change of renal biopsy pathological disease spectrum in Baotou, Inner Mongolia[J]. Journal of Baotou Medical College, 2026
, 42(1)
: 6
-10
.
DOI: 10.16833/j.cnki.jbmc.2026.01.002
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