Objective: To investigate the correlation between hyperoxaluria (oxaluria≥45 mg/d) and gender, age and metabolic diseases (hypertension, diabetes), providing evidence for the prevention and management of urinary calculi. Methods: The clinical data of 200 patients with urinary calculi admitted to Anyang Sixth People′s Hospital from April 2024 to April 2025 were retrospectively analyzed. According to the level of oxalic acid urine, the patients were divided into hyperoxaluria group (n=102) and non-hyperoxaluria group (n=98). The gender, age, hypertension and diabetes data of the two groups were collected. Univariate analysis was performed by chi-square test, and binary logistic regression analysis was performed on the factors with significant differences. Results: There were significant differences were observed between the hyperoxaluria and non-hyperoxaluria groups in gender (P＜0.001) and diabetes prevalence (P=0.024), while age and hypertension showed no significant associations(P＞0.05). Multivariate analysis revealed that males had a significantly higher risk of hyperoxaluria than females (OR=3.534, 95%CI: 1.956-6.385), while diabetic patients had a lower risk than non-diabetic patients (OR=0.505, 95%CI: 0.280-0.913). The proportion of hyperoxaluria in young, middle-aged and elderly groups was similar (51.4%, 50.0%, 51.6%). Conclusion: Gender and diabetes are independent influencing factors for hyperoxaluria, with males and non-diabetic individuals at higher risk, whereas age and hypertension showed no significant association. Clinically, male patients should prioritize oxaluria metabolism monitoring and dietary interventions, while diabetic patients require integrated management of other metabolic abnormalities to reduce the risk.
SU Wentao
,
YANG Hongliang
. Correlationanalysis between hyperoxaluria and gender, age, metabolic diseases[J]. Journal of Baotou Medical College, 2025
, 41(11)
: 82
-86
.
DOI: 10.16833/j.cnki.jbmc.2025.11.015
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