Objective: To evaluate the therapeutic efficacy of intersphincteric resection (ISR) combined with coloplasty in patients with ultra-low rectal cancer. Methods: A total of 90 rectal cancer patients who were continuously admitted to the First Affiliated Hospital of Baotou Medical College from January 2021 to December 2024 and met the inclusion and exclusion criteria were selected as the research objects. Thirty patients who underwent ISR combined with colonoscopy were selected as the observation group, and 30 patients who underwent traditional Miles and Dixon surgeries were selected as the control group 1 (M group) and control group 2 (D group). The positive rate of distal resection margin (DRM), incidence of complications, anal preservation rate, Wexner incontinence score and modified fecal incontinence quality of life (mFIQL) score were compared among the three groups. Results: There was significant difference in the resection rate of resection with microscopically negative margins (R0) among the three groups (P＜0.05), and there was significant difference between group M and group D (P＜0.05), while there was no significant difference between the observation group and the group M and group D (P＞0.05), suggesting that the effect of ISR combined surgery in achieving R0 resection was between the traditional Miles surgery and Dixon surgery. The anal preservation rate of the observation group was 100%, which was higher than that of the D group. The mean postoperative Wexner score of the observation group was lower than that of the D group at 3 months, 6 months and 9 months after operation (P＜0.05), suggesting that the anal function was better than that of the D group. The postoperative mFIQL score of the observation group was lower than that of the M group (P＜0.05), indicating that its quality of life was better than that of the latter, but there was no significant difference between the observation group and the D group (P＞0.05). Postoperative recurrence analysis showed that the recurrence rate of the observation group was lower than that of the D group (P＜0.05). Conclusion: Compared with traditional surgical methods, ISR surgery combined with coloplasty shows the same degree of tumor resection effect, as well as advantages in anus-preserving rate, postoperative anal function and quality of life.
LONG Junyu
,
ZHU Qiuping
,
SHI Xuewei
,
BAI Qingyang
. Observation on theeffect of ISR combined with colonoplasty in the treatment of ultra-low rectal cancer[J]. Journal of Baotou Medical College, 2025
, 41(10)
: 47
-51
.
DOI: 10.16833/j.cnki.jbmc.2025.10.009
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