Objective: To investigate the effects of oral nutrition supplementation 10 days before surgery on preoperative nutritional status, immune function and postoperative infectious complications in patients with oral cancer. Methods: A total of 40 elderly patients with preoperative oral cancer who were screened by Nutritional Risk Screening 2002 (NRS-2002) score were divided into observation group and control group according to random number table method, with 20 patients in each group. The two groups were given dynamic nutritional support according to the target demand of energy and protein after operation. The control group was given routine nutritional education before operation. The observation group was given Nengquansu combined with whey protein powder oral nutrition supplement on the basis of the control group. The changes of nutritional status indexes, immune function indexes and postoperative infectious complications before and after intervention were compared between the two groups. Results: After intervention, the levels of albumin and prealbumin in the observation group were significantly higher than those in the control group, and the differences were statistically significant (P＜0.05), while there was no significant difference in RBC, HB between the observation group and the control group (P＞0.05). After intervention, IgA, CD4 and CD4/CD8 of the observation group were significantly higher than those of the control group, while C-reactive protein of the observation group was significantly lower than that of the control group, the differences were statistically significant (P＜0.05). After intervention, there was no significant difference in IgG, IgM, CD3, CD8 and NK cells between the observation group and the control group (P＞0.05). After intervention, the proportion of the total number of complications in the observation group was significantly lower than that in the control group, and the difference was statistically significant (P＜0.05). Conclusion: The preoperative oral nutritional supplement of Nengquansu combined with whey protein powder can improve the preoperative nutritional status and immune function of patients with oral cancer, and reduce the incidence of postoperative infectious complications.
YUAN Feng
,
NIAN Feng
,
LIANG Yueyue
,
ZHANG Yun
,
CAO Mingming
,
BAI Yawen
,
ZHANG Kai
. Effect of preoperative oral nutrition supplementation on nutritional status and immune function in elderly patients with oral cancer[J]. Journal of Baotou Medical College, 2025
, 41(6)
: 86
-90
.
DOI: 10.16833/j.cnki.jbmc.2025.06.016
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