Objective:To study the relationship between pre-pregnancy body mass index(BMI) and gestational diabetes(GDM) and its influencing factors in Guangdong. Methods: A total of 488 women who received prenatal physical examinations from January 2015 to October 2020, in Guangdong were selected. 18 women with GDM were divided into the GDM group, and 470 women without GDM into the non-GDM group, and general data such as pre-pregnancy BMI, age, height, parity, waist circumference of all women were statistically analyzed. Results: Compared with the non-GDM group, the pre-pregnancy BMI (P＜0.05) and waist circumference (P＜0.05) in the GDM group were higher than those in the non-GDM group. There were 74 cases of normal weight gaining, 136 cases of moderate weight gaining, 112 cases of mild weight gaining, and 166 cases of severe weight gaining in the 488 pregnant women. There were no cases of GDM among 74 pregnant women within the normal range of weight gaining. There were only 1 case of GDM occurred in the 112 pregnant women with mild weight gaining, which accounted for about 0.89%. There were 4 cases GDM occurred among 136 pregnant women with moderate weight gaining (2.94%), and there were 13 cases GDM occurred among 166 pregnant women with severe weight gaining (7.83%). Logistic regression analysis showed that the BMI of pregnant women (＞26.0 kg/m2), severe weight gaining during pregnancy, waist circumference (＞74.0 cm) were risk factors for pregnant women to develop GDM. After excluding factor of weight gaining during pregnancy, Logistic regression analysis showed that there was no statistical relationship between BMI and waist circumference (＞74.0 cm) with the occurrence of GDM in pregnant women (P＞0.05). Conclusion: Prenatal BMI and waist circumference are independent risk factors for diabetes in pregnant women in Guangdong, and there is a correlation between gestational weight gaining and gestational diabetes, which has important guiding significance for adjusting prenatal BMI and controlling gestational weight gaining.
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