Objective: To explore the clinical application of the ultrasound microprobe in patients with peripheral lung cancer.Methods: A study was conducted on 83 patients with peripheral lung cancer admitted to Shenzhen Hospital, University of Chinese Academy of Sciences from January 2021 to December 2022.All patients underwent small probe ultrasound examination. Based on the pathological results as the gold standard, the patients were divided into metastatic and non metastatic groups according to the presence or absence of lymph node metastasis. The ultrasound parameters, MCVD, and MVD in the two groups were compared, and the correlation between MCVD and MVD was analyzed. The severity of the condition was evaluated based on TNM staging, and the MCVD and MVD of each group of patients were compared, and the correlation between MCVD and TNM staging was analyzed. Results: The proportion of patients with low echo, uneven echo, clear boundary, and short diameter ≥ 1.0 cm in the metastatic group was 75.00%, 85.71%, 78.57%, and 71.43%, respectively, higher than 29.09%, 40.00%, 49.09%, and 38.18% in the non metastatic group (P＜0.05). The levels of MCVD and MVD in the metastatic group were higher than those in the non metastatic group (P＜0.05). Pearson correlation analysis showed a positive correlation between MCVD and MVD (r=0.622, P＜0.05). The differences in MCVD and MVD among patients with different TNM stages were statistically significant, and they were all in stages Ⅰ<Ⅱ<Ⅲ (P＜0.05). The correlation analysis results showed a positive correlation between MCVD and TNM staging (r=0.817, P=0.013).Conclusion: The proportion of patients with peripheral lung cancer who have lymph node metastasis is low echo, uneven echo, clear boundary, short diameter ≥1.0 cm were higher. Small probe ultrasound MCVD is positively correlated with MVD and TNM staging.
PAN Xinzhen
,
WANG Tao
,
WU Yibing
,
FU Peng
. Clinical application of the ultrasound small probe in patients with peripheral lung cancer[J]. Journal of Baotou Medical College, 2024
, 40(5)
: 61
-64
.
DOI: 10.16833/j.cnki.jbmc.2024.05.012
[1] Xu CH, Wang JW, Wang W, et al. The diagnosis value of endobronchial ultrasound transbronchial lung biopsy combined with rapid on-site evaluation in peripheral lung cancer[J]. Clin Respir J, 2020, 14(5): 447-452.
[2] Xie FF, Chen JX, Jiang YF, et al. Microwave ablation via a flexible catheter for the treatment of nonsurgical peripheral lung cancer: a pilot study[J]. Thorac Cancer, 2022, 13(7): 1014-1020.
[3] Ankudavicius V, Miliauskas S, Poskiene L, et al. Diagnostic yield of transbronchial cryobiopsy guided by radial endobronchial ultrasound and fluoroscopy in the radiologically suspected lung cancer: a single institution prospective study[J]. Cancers, 2022, 14(6): 1563.
[4] Zhou BR, Yang XF, Zhang XM, et al. Ultrasound elastography for lung disease assessment[J]. IEEE Trans Ultrason Ferroelectr Freq Control, 2020, 67(11): 2249-2257.
[5] 赫捷, 李霓, 陈万青, 等. 中国肺癌筛查与早诊早治指南(2021,北京)[J]. 中国肿瘤, 2021, 30(2): 81-111.
[6] Liam CK, Lee P, Yu CJ, et al. The diagnosis of lung cancer in the era of interventional pulmonology[J]. Int J Tuberc Lung Dis, 2021, 25(1): 6-15.
[7] Liu Y, Wang F, Zhang QC, et al. Value of virtual bronchoscopic navigation and transbronchial ultrasound-guided sheath-guided exploration in diagnosis of peripheral lung cancer[J]. World J Clin Cases, 2020, 8(16): 3450-3457.
[8] Zou XW, Zhu YL, Hu Q, et al. Diagnostic value of ultrasound-guided transbronchial lung biopsy in peripheral tuberculous pulmonary lesions[J]. Diagn Cytopathol, 2022, 50(12): 572-578.
[9] 王磊, 于丽, 任法云. CT增强扫描对中央型肺癌术前分期的诊断价值[J]. 癌症进展, 2020, 18(24): 2520-2522.
[10] Safai Zadeh E, Beutel B, Dietrich CF, et al. Perfusion patterns of peripheral pulmonary lesions in COVID-19 patients using contrast-enhanced ultrasound (CEUS):acase series[J]. J Ultrasound Med, 2021, 40(11): 2403-2411.
[11] Steinfort DP, Herth FJF. Bronchoscopic treatments for early-stage peripheral lung cancer: are we ready for prime time[J]. Respirology, 2020, 25(9): 944-952.
[12] Dziedzic R, Marjański T, Rzyman W. A narrative review of invasive diagnostics and treatment of early lung cancer[J]. Transl Lung Cancer Res, 2021, 10(2): 1110-1123.
[13] Ye RZ, Zhou XL, Shao F, et al. Feasibility of a 5G-based robot-assisted remote ultrasound system for cardiopulmonary assessment of patients with coronavirus disease 2019[J]. Chest, 2021, 159(1): 270-281.
[14] Lachkar S, Perrot L, Gervereau D, et al. Radial-EBUS and virtual bronchoscopy planner for peripheral lung cancer diagnosis: how it became the first-line endoscopic procedure[J]. Thorac Cancer, 2022, 13(20): 2854-2860.
[15] Ishiwata T, Motooka Y, Ujiie H, et al. Endobronchial ultrasound-guided bipolar radiofrequency ablation for lung cancer: a first-in-human clinical trial[J]. J Thorac Cardiovasc Surg, 2022, 164(4): 1188-1197. e2.
