Objective: To investigate the prevalence and risk factors of Candida albicans, Candida tropicalis and Candida krusei in patients with gastritis. Methods: Relevant data of patients were collected by questionnaires, and mucosal samples and gastric juices of digestive tract of gastritis patients were collected under aseptic operation for isolation and identification, so as to explore the colonization and/or infection of candida in gastritis patients. Results: A total of 57 patients with gastritis were collected, including 2 patients with missing demographic characteristics and clinical information. Among the 55 patients, 25 (45.45 %) were HP-positive and 30 (54.55 %) were HP-negative. There were 15 patients (27.27 %) with atrophic gastritis and 33 patients (60.00 %) with non-atrophic gastritis. The main candida species in the upper digestive tract of gastritis patients were Candida albicans and Candida chrysalis, followed by Candida tropicalis, and the proportion of Candida glabrata was relatively low. In the samples of the lower digestive tract, the main candida genus was Candida Chrysalis, followed by Candida tropicalis and Candida albicans. Some patients with gastritis showed mixed positive candida. Conclusion: The strains of upper and lower digestive tract were different in patients with gastritis. The positive rate of candida was not significantly correlated with age, sex or type of gastritis (P＞0.05). Hp infection may be a risk factor for candida infection in gastritis patients.
ZHANG Yang
,
HAO Jinqi
,
YU Yanqin
,
DING Ruifeng
,
LI Min
,
ZHANG Lixia
,
HAO Yong
,
SHI Jihai
. Isolation, identification and colonization analysis of Candida strains in digestive tract of gastritis patients[J]. Journal of Baotou Medical College, 2023
, 39(12)
: 26
-30
.
DOI: 10.16833/j.cnki.jbmc.2023.12.005
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