Evaluation value of ultrasound elastography on esophageal and gastric varices in liver cirrhosis

  • LI Gang ,
  • YAN Guozhen ,
  • WANG Yuan ,
  • ZHU Ruohan ,
  • ZHANG Xue
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  • 1. Department of Ultrasound, the First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou 014010, China;
    2. Department of Ultrasound, the Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology

Received date: 2023-06-27

  Online published: 2023-09-22

Abstract

Objective: To investigate the application value of sound touch elastography and sound touch quantify of liver and spleen in the evaluation of esophageal and gastric varices(EGV) in liver cirrhosis. Methods: A total of 87 patients with liver cirrhosis were collected and divided into the non-varices group (44 cases), mild varices group (13 cases) and moderate to severe varices group (30 cases) based on gastroscopic results. Ultrasonic elastography were used to measure the values of liver sound touch elastography (L-STE), liver sound touch quantify (L-STQ), spleen sound touch elastography (S-STE), and spleen sound touch quantify (S-STQ). STE and STQ indexes of liver and spleen were compared in each group. The receiver operating characteristic (ROC) curve was drawn to analyze the diagnostic efficacy of each parameter, and the area under the curve (AUC) was calculated. Results: There were significant differences in the STE and STQ values of liver and spleen between the non-varicose group and the varicose groups (P<0.05). Spearman correlation coefficient was used for correlation analysis, and the values of L-STE, L-STQ, S-STE and S-STQ were positively correlated with the degree of esophageal and gastric varices (r=0.505, 0.487, 0.558,0.535). The AUCs of L-STE, L-STQ, S-STE and S-STQ for diagnosing EGV were 0.788,0.770, 0.804 and 0.785, and the optimal cut-off values for predicting EGV were 9.29 kPa, 13.58 kPa, 23.34 kPa and 26.44 kPa, respectively. L-STE, L-STQ, S-STE, S-STQ values predicted the AUC of mild varicose veins was 0.781, 0.730, 0.721, 0.692, all P<0.05. The areas under the curve of L-STE, L-STQ, S-STE and S-STQ predicted moderate and severe varicose were 0.831, 0.828, 0.873 and 0.862(P<0.05). Conclusion: Using STE and STQ to measure liver and spleen stiffness has good predicting value to EGV in live cirrhosis. The shear wave elastic hardness of liver and spleen increasing with the severity of EGV in liver cirrhosis can be used as an effective index to determine the severity of varicosity.

Cite this article

LI Gang , YAN Guozhen , WANG Yuan , ZHU Ruohan , ZHANG Xue . Evaluation value of ultrasound elastography on esophageal and gastric varices in liver cirrhosis[J]. Journal of Baotou Medical College, 2023 , 39(9) : 44 -48 . DOI: 10.16833/j.cnki.jbmc.2023.09.009

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