Objective: To investigate the effect of early oral enteral nutrition (EN) on the recovery of patients after laparoscopic colorectal cancer surgery. Methods: Patients who were scheduled for laparoscopic radical colorectal cancer surgery in our hospital from May 2021 to February 2022 were prospectively enrolled and randomly divided into the observation (EN) group and the control (non-EN) group. The observation group was given oral enteral nutrition from the first day after surgery, and the concentration and dose were adjusted over time to full dose. The control group was given equal volume of hot water for drinking, then the liquid diet was given after ventilation, and gradually transitioned to normal diet. The indicators of nutrition, inflammation, and intestinal barrier function were measured on the 7th day after surgery. The postoperative exhaust time, bowel movement, off-bed time, and hospital stay of the two groups were recorded. Results: A total of 100 patients were cured and discharged. Time to return to normal diet (t=4.658; P＜0.05) and postoperative hospital days (t=6.304; P＜0.05) of the observation group were significantly shorter than those in the control group. On 7th day after surgery, no significant differences were observed in nutritional indicators such as levels of hemoglobin and albumin between the two groups (P＞0.05), but the levels of peripheral white blood cell count (t=4.973; P＜0.05), C-reactive protein (t=5.075; P＜0.05), and neutrophil count (t=7.597; P＜0.05) in the observation group were significantly lower than those in the control group. The levels of diamine oxidase (t=18.457; P＜0.05) and fecal calprotectin (t=9.142; P＜0.05) of the observation group were significantly lower than those in the control group. The levels of zonula occludens-1 of the observation group were significantly higher in than control group(t=18.141; P＜0.05). Conclusion: Early oral enteral nutrition after laparoscopic radical colorectal cancer surgery can promote postoperative gastrointestinal function recovery and improve postoperative recovery.
QIU Quanwei
,
YANG Yiqun
,
LIU Quanli
,
LI Wenjie
,
XU Mengzhen
,
ZUO Lugen
,
LIU Mulin
. Effect of oral enteral nutrition on postoperative recovery after laparoscopic colorectal cancer resection: a clinical study[J]. Journal of Baotou Medical College, 2023
, 39(9)
: 40
-43
.
DOI: 10.16833/j.cnki.jbmc.2023.09.008
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