Objective: To explore the effect of multidisciplinary nursing on pulmonary rehabilitation of lung cancer patients after lobectomy.Methods: 80 lung cancer patients who underwent lobectomy from March 2016 to February 2017 were chosen and randomly divided into the observation group and the control group, 40 patients in each group. The control group was treated with routine specialist care while the observation group was treated with multidisciplinary care, with lung function indexes, 6 minutes walk test (6MWT), the postoperative pulmonary complication rate and postoperative hospitalization time compared.Results: The postoperative respiratory rate was significantly lower in the observation group than that in the control group(t=2.341, P=0.015); maximal voluntary ventilation (MVV), forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC and 6MWT after operation in the observation group were significantly higher than those in the control group (P＜0.05). The incidence rates of pulmonary infection, atelectasis and respiratory failure were lower and the average hospital stay was shorter in the observation group than those in the control group (P＜0.05).Conclusion: Multidisciplinary care can improve lung rehabilitation after lobectomy quickly and effectively, reduce the incidence of pulmonary complications, shorten the hospital stay and improve the quality of care.