Objective: To screen the formulation process of the cream preparation of ellagic acid from pomegranate extract. Methods: The dosages of glyceryl monostearate, white petrolatum and liquid paraffin, which had the greatest influence on matrix formability were taken as factors, and the preparation process of pomegranate extract ellagic acid cream was optimized by the orthogonal experiment method. Results: The optimized cream base formulation was stearyl alcohol 0.8 g, white petrolatum 1.8 g, liquid paraffin 0.6 g, glycerol monostearate 1.2 g, sodium lauryl sulfate 0.1 g, glycerol 1.0g and purified water 8.5 g; the cream prepared by fusion method had good stability, uniform color, fine lubrication and no irritation. Conclusion: The preparation process of the cream is simple and feasible, the quality is stable and reliable, and it is suitable for the preparation of pomegranate extract ellagic acid cream.
LIU Yue
,
FAN Gaofu
,
YAO Qiqi
,
HU Ting
,
ZHENG Bin
. Preliminary study on the preparation technology of pomegranate extract ellagic acid cream[J]. Journal of Baotou Medical College, 2023
, 39(6)
: 88
-91
.
DOI: 10.16833/j.cnki.jbmc.2023.06.018
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