Efficacy of traditional Chinese herbal drugs in the treatment of pressure ulcer: a meta-analysis

  • WANG Xinxin ,
  • CHEN Xiaoyan ,
  • LI Sijia ,
  • ZHANG Wenlian ,
  • JIA Jianxin ,
  • DOU Deqiang
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  • 1. Liaoning University of Traditional Chinese Medicine,Liaoning 110847,China;
    2. Basic Medical and Forensic Medicine, Baotou Medical College;
    3. First Affiliated Hospital of Baotou Medical College

Received date: 2023-01-04

  Online published: 2023-06-30

Abstract

Objective: To explore the role of Chinese medicine external treatment on pressure ulcer. Methods: Randomized and controlled trials with Chinese medicine external treatment as cure method and modern medicine method as compared, were gathered from Pubmed, Sinomed, EMBASE, CNKI, Wanfang and VIP databases since initial to Jun 2022. Review Manager 5.2 software was employed to analyse data. Results: A total of 30 studies involving 2 170 participants consist of 1 159 test and 1 011 control were included. Data indicated the cure rate and effective rate of test group were both more excellent than control group (RR=1.66, 95 %CI[1.51, 1.81], P<0.000 01, RR=1.24, 95 %CI[1.11, 1.37], P<0.000 1), the cure time of test group was more shorter (MD=-9.06, 95 %CI[-14.45, -3.68], P=0.001 0), the PUSH score of test group was also more lower(MD=-0.99, 95 %CI[-1.44, -0.55], P<0.000 1). Conclusion: External therapy with Chinese medicine has certain advantages in treating pressure ulcer.

Cite this article

WANG Xinxin , CHEN Xiaoyan , LI Sijia , ZHANG Wenlian , JIA Jianxin , DOU Deqiang . Efficacy of traditional Chinese herbal drugs in the treatment of pressure ulcer: a meta-analysis[J]. Journal of Baotou Medical College, 2023 , 39(6) : 83 -87 . DOI: 10.16833/j.cnki.jbmc.2023.06.017

References

[1] 姜德友, 蒋钱福, 穆欣, 等.褥疮源流考[J/OL].辽宁中医杂志: 1-8[2022-11-04]. http://kns.cnki.net/kcms/detail/21.1128.R.20220614.1152.002. html.
[2] 郑明凤.中医综合外治法治疗压疮的疗效观察[J].中医临床研究, 2021, 13(10): 72-74.
[3] 王欣欣, 刘季平, 李思佳, 等.中药治疗特应性皮炎疗效和安全性的系统评价[J].中国免疫学杂志, 2019, 35(24): 3054-3059.
[4] 王静."褥疮散"外敷结合光子治疗仪治疗Ⅲ期褥疮32例临床研究[J].江苏中医药, 2016, 48(2): 49-50.
[5] 杨志芬, 植秋婵, 关素芳, 等.复方地牯牛散治疗褥疮的临床护理研究[J].中国实用医药, 2008, 3(27): 175-176.
[6] 李清云.复方中药煎剂治疗Ⅱ、Ⅲ期褥疮疗效观察[J].四川中医, 2001, 19(1): 52-53.
[7] 施捷, 金杰.红油膏、白玉膏、玉白散贯序外敷治疗褥疮的临床疗效观察[J].中国民族民间医药, 2010, 19(4): 91-92.
[8] 尹兰云, 袁素芹.双黄紫血蚓封闭式外敷治疗深度褥疮60例[J].四川中医, 2002, 20(8): 61-62.
[9] 陈佩仪, 眭道顺.外敷生肌玉红膏治疗压疮18例疗效观察[J].新中医, 2008, 40(6): 45-46.
[10] 罗郴.云南白药粉剂外敷治疗褥疮的效果观察[J].当代护士(专科版), 2008, (9): 69-70.
[11] 李秀华.云南白药联合利凡诺尔外敷治疗Ⅱ度以上褥疮的应用研究[J].现代诊断与治疗, 2013, 24(16): 3643.
[12] 彭亚兰.云南白药治疗褥疮疗效分析[J].中国现代药物应用, 2011, 5(1): 110.
[13] 黄琳.中药辨证分层换药治疗难治性褥疮的疗效观察[J].湖北中医杂志, 2012, 34(3): 12-13.
[14] 闵雅莲, 姚爱丽, 王海韵.中药疮疡膏治疗褥疮的效果观察和评价[J].蚌埠医学院学报, 2004, 29(2): 182-183.
[15] 黄春艳.中药防疹散治疗褥疮的疗效观察[J].中国保健营养, 2012, 22(12): 2307.
[16] 洪潆, 高美秀.中药合剂外用治疗Ⅲ期与Ⅳ期褥疮40例[J].中国中医药现代远程教育, 2014, 12(13): 22-24.
[17] 董兴刚, 张敏, 冯健, 等.中药金疮油膏治疗难治性压疮临床疗效观察[J].中国中西医结合杂志, 2017, 37(2): 155-159.
[18] 徐红英.中药芦荟治疗褥疮的探讨[J].护理研究, 2004, 18(2): 158.
[19] 陈利萍.中药祛腐生肌散治疗褥疮的护理研究[J].医学信息: 中旬刊, 2010, 5(9): 2631-2632.
[20] 匡先琼, 高卫华.中药褥疮合剂治疗与护理褥疮40例临床观察[J].湖北中医杂志, 2011, 33(3): 62-63.
[21] 张金先, 张月珍, 边瑞宏.中药渗敷治疗Ⅲ期褥疮62例[J].中医外治杂志, 2001, 10(1): 18.
[22] 袁曙云.中药湿敷治疗Ⅲ期褥疮62例[J].现代中西医结合杂志, 2003, 12(21): 2342.
[23] 宋易华, 陈琳, 江立军.中药外敷治疗褥疮30例[J].吉林中医药, 2006, 26(8): 27.
[24] 杨丽华, 闫家平.中药洗剂治疗褥疮的效果观察[J].实用医技杂志, 2015, 22(8): 881-882.
[25] 骆玉乔, 李士敏.中药治疗褥疮的疗效观察[J].天津中医药, 2008, 25(5): 390.
[26] 袁震宇.中药紫色消肿膏治疗褥疮46例临床观察[J].临床心身疾病杂志, 2015, 21(S2): 310-311.
[27] 孙艳丽.中医治疗压疮外用药用药规律及复方黄柏液临床疗效观察研究[D].北京: 北京中医药大学, 2015.
[28] 刘宏旭, 李海玲.紫草油膏外用治疗褥疮45例观察[J].新疆中医药, 2011, 29(3): 26.
[29] 于淼淼.疮疡平软膏外敷治疗褥疮疗效的临床讨论[D].沈阳: 辽宁中医药大学, 2009.
[30] 赵忠辉, 潘平, 郭永林, 等.定痛生肌散合生肌玉红膏治疗褥疮疗效观察[J].实用中医药杂志, 2013, 29(11): 938.
[31] 吴敏, 张月娟, 余艳兰, 等.象皮生肌膏联合艾灸治疗Ⅲ期压疮合并糖尿病的疗效观察[J].中医药导报, 2018, 24(7): 81-83.
[32] Chotchoungchatchai S, Krairit O, Targulpiankit P, et al. The efficacy of honey and a Thai Herbal Oil preparation in the treatment of pressure ulcers based on Thai traditional medicine wound diagnosis versus standard practice: an open-label randomized controlled trial[J]. Contemp Clin Trials Commun, 2020,17:100538.
[33] Liu J, Cai M F, Yan H M, et al. Yunnan Baiyao reduces hospital-acquired pressure ulcers via suppressing virulence gene expression and biofilm formation of Staphylococcus aureus[J]. Int J Med Sci, 2019,16(8):1078-1088.
[34] 盛永旭, 李大勇.褥疮中西医治法的研究进展[J].智慧健康, 2022, 8(16): 29-34.
[35] 潘礼刚, 刘曼, 陈烨, 等.湿润烧伤膏联合重组人碱性成纤维细胞生长因子对浅Ⅱ度烧伤患者创面肉芽组织HIF-1α、VEGF蛋白表达的影响[J].现代生物医学进展, 2021, 21(23): 4478-4482.
[36] 黄丹, 张乐园, 袁光洪, 等.虎黄烧伤搽剂治疗Ⅲ期褥疮临床疗效评价[J].中医药临床杂志, 2019, 31(12): 2337-2339.
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