Objective: To explore a more economical and effective clinical method for the treatment of Venous leg ulcer (VLU). Methods: The data of 13 patients with VLU treated in outpatient of Burhantu Health Centre in Kundurun district from December 2020 to October 2022 were analyzed retrospectively. All of them were diagnosed with unilateral limb disease, with a total of 16 ulcers, including 11 cases of internal ulcer and 2 cases of external ulcer. There were 10 males and 3 females, aged 45 to 72, with an average age of 59.27 years. Based on the pathogenetic characteristics of "Deficiency-Blood Stasis-Change", the 13 VUL patients were treated with Buyang Huanwu Decoction plus or minus oral decoction, adding necessary wound treatment and external application of Shengji Yuhong ointment. Results: The symptoms of the 13 VLU patients were significantly improved in a short time, the sores healed quickly, and no scars left after healing. No relapse in these 13 patients were found through the follow-up until the date of this paper being finished. Conclusion: VLU has the pathogenetic characteristics of "Deficiency - Blood stasis - Change". "Deficiency - Blood stasis" is the basic pathogenesis of VLU, and Dampness to Heat to Toxin is the change based on "Deficiency - Blood stasis". Based on the pathogenetic characteristics of "Deficiency - Blood Stasis - Change", the clinical effect is visibly in treating VLU with Buyang Huanwu Decoction to supplement qi and activate blood, combined with the external use of Shengji Yuhong Ointment .