Correlation between Coronary Artery Disease and NHR and MHR in Patients with ACS Complicated with T2DM

  • LI Ping ,
  • ZHAO Ruiping ,
  • YU Ye
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  • 1. Baotou Medical College, Baotou 014040, China;
    2. Department of Cardiology, Baotou Central Hospital

Received date: 2022-06-09

  Online published: 2023-03-08

Abstract

Objective: To investigate the relationship between the severity of coronary artery disease and the ratio of neutrophil to high density lipoprotein (NHR) and monocyte to high density lipoprotein (MHR) in patients with ACS complicated with T2DM. Methods: One hundled and fifty one patients who were diagnosed as ACS combining with T2DM by CAG in Baotou Central Hospital from June 2019 to June 2021 were selected as study objects. All selected patients were divided into mild group (Gensini score ≤40) (69 cases) and severe group (Gensini score > 40) (82 cases) based on the severity of coronary artery disease. Results: NHR and MHR in the severe group were higher than those in the mild group, and the difference was statistically significant. MNR and NHR were positively correlated with Gensini score in ACS patients combined with T2DM. Multivariate logistic analysis showed that increased NHR was a risk factor for the severity of ACS complicated with T2DM coronary artery disease. The best value of ROC curve for NHR to predict the severity of coronary artery disease in ACS patients with T2DM was 5.276, with a sensitivity of 61.0 %, and a specificity of 94.2 %. The AUC for NHR was 0.726. Conclusion: The severity of coronary artery disease in ACS patients combined with T2DM is positively correlated with NHR and MHR.

Cite this article

LI Ping , ZHAO Ruiping , YU Ye . Correlation between Coronary Artery Disease and NHR and MHR in Patients with ACS Complicated with T2DM[J]. Journal of Baotou Medical College, 2023 , 39(2) : 31 -35 . DOI: 10.16833/j.cnki.jbmc.2023.02.006

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