Objective: To investigate the correlation between eosinophil (EOS) count in nasal polyp and recovering process of CRSwNP (Chronic rhinosinusitis with polyps, CRSwNP) patients at different ages after nasal endoscopic surgery. Methods: 204 CRSwNP patients were selected and divided into the adolescent group, adult group and elderly group. Messerklinger was used to remove nasal polyps and open sinuses. Patients with deviated septum affecting nasal drainage were given septal correction simultaneously. Radiofrequency ablation was performed on patients with the inferior turbinate hypertrophy. Surgical specimens were given pathological examination, and EOS was counted under the microscope after HE staining. VAS score for nasal congestion, nasal leakage, head and face swelling pain, olfaction, and dizziness, CT and Lund-Kennedy score were performed 0.5 month, 1 month, 3 months, 6months and 12 months after surgery. SPSS18.0 was used to compare and analyze correlation among variables. Results: EOS counts were significantly correlated with scores of nasal congestion, rhinorrhea, dizziness (0.5 month, 1 month, 3 months, 6 months and 12 months after surgery), olfaction, head and face swelling pian (0.5 month, 3 months, 6 months and 12 months after surgery) (P＜0.01). However, head and face swelling pain, olfaction (1 month after surgery) and EOS counts had no correlation (P＞0.05). There was a correlation between EOS counts and CT results and endoscopic scores (P＜0.01). The scores of nasal congestion (3 months, 6 months and 12 months after surgery) , rhinorrhea(0.5 month, 1 month, 3 months, 6 months and 12 months after surgery), head and face swelling pain(3 months, 6 months and 12 months after surgery) , dizziness (0.5 month, 6 months and 12 months after surgery) in the adolescents had higher symptom scores than the other two groups(P＜0.05). Meanwhile, there was no significant correlation between the adolescents with the other groups on nasal congestion(P＞0.05). Conclusion: EOS counts is correlated with efficacy at different time windows. postoperative symptom scores of adolescents are higher than those of the other two groups, suggesting that follow-up intervention should be enhanced after surgery to reduce recurrence.