Objective: To investigate the regularity and risk factors of central lymph node metastasis (CLNM) in patients with multifocal papillary thyroid carcinoma (MPTC). Method: The clinicopathological data of 107 patients with MPTC admitted to the Affiliated Hospital of Qingdao University from January 2015 to May 2017 were retrospectively analyzed, including gender, age, tumor location, whether the dorsal membrane was invaded, whether Hashimoto' s thyroiditis was complicated, the total diameter of the tumor and the number of the tumor. The central lymph node metastasis (CLNM) and its risk factors in MPTC patients were discussed. Results: Among 107 MPTC patients, 56 patients (52.3 %) had central lymph node metastasis. The number of prophylactic central lymph node dissection was 1-22, with an average of (5.61±3.83), and the number of metastasis was 0-10, with an average of (1.36±1.95). Univariate analysis showed that dorsal membrane invasion, gender, age (<45 years old), number of cancer foci, and total diameter of cancer foci ＞ 1cm were risk factors for central lymph node metastasis in MPTC patients. Multivariate analysis showed that the number of cancer foci, total diameter of cancer foci, dorsal membrane invasion, age and male were independent risk factors for central lymph node metastasis in MPTC patients (P＜0.05). Conclusion: Multifocality is a risk factor for central lymph node metastasis in papillary thyroid carcinoma. For MPTC patients, especially those with total tumor diameter ＞ 1 cm, dorsal membrane invasion, age (＜45 years ) and male patients, total thyroidectomy and ipsilateral central lymph node dissection are recommended.
LI Wei
,
AN Shucai
,
WANG Lei
,
WANG Zhihao
,
LI Ling
. Analysis of the risk factors of lymph node metastasis in central cervical area of multifocalpapillary thyroid microcarcinoma[J]. Journal of Baotou Medical College, 2022
, 38(10)
: 51
-54
.
DOI: 10.16833/j.cnki.jbmc.2022.10.010
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