Objective: To explore the influence of patient-controlled epidural analgesia and timing of pump closure on the second stage of maternal labor.Methods: 198 cases of maternal were selected as observation objects, and were randomly divided into three groups, with 66 cases in each group. In group A, the analgesic pump was closed when the cervix was open at about 8 ~ 9cm, in group B the analgesic pump was closed when the cervix was open completely, and in group C the epidural analgesia were not performed. The analgesic effect and the influence on labor stage and delivery outcome in the three groups were compared.Results: The analgesic effects in group A and B were significantly higher than that in group C, the second stage of labor was significantly longer than that in group C (P＜0.05). The second stage of labor in group A and B was significantly different (P＜0.05), but there were no significant differences in other indexes (P＞0.05); There were no significant differences in the 2h postpartum bleeding, neonatal Apgar score, cesarean section rate and other clinical outcome indexes between the three groups (P＞0.05).Conclusion: The patient-controlled epidural analgesia can relieve the pain of maternal, and can shorten the second stage of labor with the analgesia pump closed when the cervix was open at about 8 ~ 9cm. It has no adverse effects on maternal and neonatal outcomes.