Objective: To study the clinical effects of transurethral resection (TURP), transurethral resection of prostate (TUVP) and selective transurethral holmium laser vaporization prostatectomy (PVP) in the treatment of prostatic hyperplasia.Methods: 121 cases of prostatic hyperplasia patients were divided into TURP group (n=40), TUVP group (n=41) and PVP group (n=40). The operation time, intraoperative blood loss, postoperative bladder irrigation time, indwelling catheter time and hospitalization time were observed and compared in the three groups. IPSS, Qmax, prostate size and other indicators before and after surgery were compared statistically during the 1-3 months' follow-up. Results: The operation time in PVP group was longer, but the amount of bleeding, rinse time, extubation time and hospitalization time were significantly better than those in TURP group and TUVP group (P＜0.05). IPSS and Qmax after operation in the three groups significantly increased (P＜0.01), but there was no statistically significant difference of other postoperative indicators between the three groups (P＞0.05). The postoperative residual prostate gland size in PVP group was significantly higher than that in TURP and TUVP group (P＜0.05). The incidence of postoperative complications in PVP group was lower than that in TURP and TUVP group (P＜0.05); but the complication incidence rate in TUVP group was lower than that in TURP group (P＜0.05).Conclusion: Compared with TURP, TUVP has obvious advantage, with relatively low incidence of complications. Although PVP has a long operation time, it has the smallest incision and the least complications in the three surgical procedures, especially for the elderly and high-risk BPH population. But the disadvantage of PVP is the higher recurrence rate of prostate.