目的：观察OxfordⅢ单髁置换术(UKA术)与全膝关节置换术(TKA术)治疗膝关节内侧间室骨关节炎的临床效果。方法：选取包头市第四医院2018年1月至2021年1月收治的66例膝关节内侧间室骨关节炎患者的临床资料,按手术方法的不同分为观察组与对照组(各33例),观察组行UKA术治疗,对照组行TKA术治疗,比较两组手术相关指标,分别于术前、术后1年比较两组股骨-胫骨角(FTA)与膝关节活动度(ROM),分别采用视觉模拟评分法(VAS)与美国特种外科医院膝关节评分(HSS)评估其疼痛与膝关节功能,并两组并发症发生情况。结果：观察组手术时间、切口长度及住院时间短于对照组,术中出血量少于对照组(P＜0.05);术前,两组FTA、ROM、VAS评分、HSS评分比较无明显差异(P＞0.05);术后1年,两组FTA、VAS评分明显低于术前,且观察组低于对照组(P＜0.05);术后1年,两组ROM、HSS评分高于术前,且观察组高于对照组(P＜0.05);观察组术后持续疼痛、假体脱落、关节僵硬、外侧间室骨关节炎等并发症总发生率(9.09%)低于对照组(30.30%)(P＜0.05)。结论：与TKA治疗比较,UKA治疗膝关节内侧间室骨关节炎更具创伤小、手术时间短、术中出血量少、术后恢复快优势,更改善患者股骨-胫骨角、膝关节活动度及膝关节功能,有效减轻患者疼痛并减少术后并发症,缩短住院时间,因此值得推广应用。

Objective: To observe the clinical effects of Oxford Ⅲ unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) in the treatment of medial compartment osteoarthritis of the knee joint. Methods: The clinical data of 66 patients with medial compartment osteoarthritis of the knee admitted to the Fourth Hospital of Baotou from January 2018 to January 2021 were selected and divided into observation group and control group (33 patients in each group) according to different surgical methods. The observation group was treated with UKA, and the control group was treated with TKA. The surgical related indexes of the two groups were compared. The femoral-tibial angle (FTA) and range of motion (ROM) of the two groups were compared before and 1 year after operation. The pain and knee function were evaluated by visual analogue scale (VAS) and Hospital for Special Surgery knee score (HSS). And the complications of the two groups. Results: The operation time, incision length and hospitalization time of the observation group were shorter than those of the control group, and the intraoperative blood loss was less than that of the control group (P＜0.05). Before operation, there was no significant difference in FTA, ROM, VAS score and HSS score between the two groups (P＞0.05), while the FTA and VAS scores of the two groups at 1 year after operation were significantly lower than those before operation, and those of the observation group were lower than the control group (P＜0.05). At 1 year after operation, the ROM and HSS scores of the two groups were higher than those before operation, and those of the observation group were higher than the control group (P＜0.05). The total incidence of postoperative complications such as persistent pain, prosthesis shedding, joint stiffness, and lateral compartment osteoarthritis in the observation group (9.09%) was lower than that in the control group (30.30%) (P＜0.05). Conclusion: Compared with TKA, UKA has the advantages of less trauma, shorter operation time, less intraoperative blood loss and faster postoperative recovery in the treatment of medial compartment osteoarthritis of knee joint. Meanwhile, it can improve the femoral-tibial angle, knee joint mobility and knee joint function, effectively reduce the pain of patients, reduce postoperative complications and shorten the hospitalization time. Therefore, it is worthy of popularization and application.