临床医学

经颅微电流刺激疗法联合文拉法辛缓释剂治疗躯体形式障碍患者的临床对照研究

  • 张集慧 ,
  • 陈波 ,
  • 王丹丹
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  • 国药北方医院心理科,内蒙古包头 014030

收稿日期: 2022-09-13

  网络出版日期: 2023-08-31

A comparative study of cranial electrotherapy stimulation combined with Venlafaxine sustained-release capsules in the treatment of somatoform disorders

  • ZHANG Jihui ,
  • CHEN Bo ,
  • WANG Dandan
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  • Psychology Department, the North Hospital of Sinopharm Group, Baotou 014030, China

Received date: 2022-09-13

  Online published: 2023-08-31

摘要

目的: 探讨经颅微电流刺激疗法(CES)治疗躯体形式障碍的临床辅助效果。方法: 选取2018年10月-2019年12月于本院住院治疗的62例躯体形式障碍患者,随机分为研究组与对照组,对照组采用文拉法辛缓释剂治疗,研究组采用文拉法辛缓释剂联合经颅微电流刺激疗法(CES),治疗前与治疗后采用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、症状自评量表(SCL-90)、躯体化症状自评量表(SSS)来评估临床疗效及不良反应发生情况。结果: 研究组的临床疗效显著优于对照组(χ2=2.132,P<0.05);与治疗前比较,治疗后2、4及8周时两组患者HAMD评分、HAMA评分、SCL-90评分和SSS评分均显著降低;治疗2、4及8周时研究组患者的HAMD、HAMA评分均显著低于对照组(t1=4.636,t2=2.159,P<0.05;t1=6.207,t2=4.693,P<0.001;t1=3.224,t2=3.414,P<0.01);治疗2、4及8周时,研究组患者SCL-90评分显著低于对照组(t1=5.201,t2=7.006,t3=6.374,P<0.001),且SSS评分也显著低于对照组(t1=2.803,t2=2.834,t3=3.485,P<0.01);研究组不良反应的总发生率为35.48 %,对照组为63.33 %,研究组不良反应总发生率显著低于对照组(χ2=4.731,P<0.05)。结论: 与仅应用文拉法辛缓释剂相比,经颅微电流刺激疗法联合文拉法辛缓释剂治疗患者的躯体形式障碍有显著的优势,值得临床推广和应用。

本文引用格式

张集慧 , 陈波 , 王丹丹 . 经颅微电流刺激疗法联合文拉法辛缓释剂治疗躯体形式障碍患者的临床对照研究[J]. 包头医学院学报, 2023 , 39(7) : 61 -65 . DOI: 10.16833/j.cnki.jbmc.2023.07.012

Abstract

Objective: To investigate the effects of cranial electrotherapy stimulation combined with capsules. Methods: A total of 62 patients with somatoform disorders in our hospital from October 2018 to December 2019 were selected. A total of 62 patients were randomly divided into study group and control group. The control group was treated with capsules, and the study group was treated with capsules combined with cranial electrotherapy stimulation. HAMD, HAMA, SCL-90 and SSS were used to evaluate the clinical efficacy and the occurrence of adverse reactions before and after treatment. Results: The clinical efficacy of the study group was significantly better than that of the control group(2=2.132,P<0.05); HAMD, HAMA , SCL-90 and SSS of two groups were significantly decreased after 2, 4 and 8 weeks of treatment. HAMD and HAMA in the study group were significantly lower than those in the control group 2, 4 and 8 weeks of treatment(t1=4.636,t2=2.159, P<0.05; t1=6.207,t2=4.693, P<0.001; t1=3.224,t2=3.414, P<0.01); 2, 4 and 8 weeks of treatment, SCL-90 in the study group was significantly lower than that in the control group(t1=5.201,t2=7.006,t3=6.374, P<0.001), and the SSS was significantly lower than the control group(t1=2.803,t2=2.834,t3=3.485, P<0.01). The total incidence of adverse reactions was 35.48 % in the study group and 63.33 % in the control group, and the difference was statistical significant (χ2=4.731, P<0.05). Conclusion: Cranial electrotherapy stimulation combined with capsules has significant advantages in the treatment of patients with somatoform disorders, which is worthy of clinical promotion and application.

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